C1RL (complement C1r subcomponent like) - Rat Genome Database

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Gene: C1RL (complement C1r subcomponent like) Pan paniscus
Analyze
Symbol: C1RL
Name: complement C1r subcomponent like
RGD ID: 11757322
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN innate immune response (inferred); proteolysis (inferred); zymogen activation (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 21 (ortholog); Ehlers-Danlos syndrome periodontal type 1 (ortholog); Ehlers-Danlos syndrome periodontal type 2 (ortholog); FOUND IN blood microparticle (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: complement C1r subcomponent-like protein-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,659,388 - 12,674,252 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,656,147 - 12,671,009 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,224,675 - 7,239,524 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,139,831 - 7,155,259 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,139,094 - 7,155,196 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
C1RL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,659,388 - 12,674,252 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,656,147 - 12,671,009 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,224,675 - 7,239,524 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,139,831 - 7,155,259 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,139,094 - 7,155,196 (-)Ensemblpanpan1.1panPan2
C1RL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38127,094,554 - 7,109,214 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl127,089,587 - 7,109,238 (-)EnsemblGRCh38hg38GRCh38
GRCh37127,247,150 - 7,261,810 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,138,291 - 7,153,069 (-)NCBINCBI36Build 36hg18NCBI36
Build 34127,138,291 - 7,153,069NCBI
Celera128,823,225 - 8,838,082 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef127,060,052 - 7,074,714 (-)NCBIHuRef
CHM1_1127,246,121 - 7,260,895 (-)NCBICHM1_1
T2T-CHM13v2.0127,107,640 - 7,122,399 (-)NCBIT2T-CHM13v2.0
C1rl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,470,072 - 124,487,602 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,470,072 - 124,487,602 (+)EnsemblGRCm39 Ensembl
GRCm386124,493,113 - 124,510,643 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,493,113 - 124,510,643 (+)EnsemblGRCm38mm10GRCm38
MGSCv376124,443,131 - 124,460,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,458,753 - 124,476,262 (+)NCBIMGSCv36mm8
Celera6126,182,904 - 126,200,439 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.16NCBI
C1rl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,080,495 - 159,097,066 (+)NCBIGRCr8
mRatBN7.24157,394,183 - 157,410,771 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,394,200 - 157,410,134 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,616,738 - 163,633,427 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,399,649 - 159,416,336 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,045,782 - 158,062,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,108,190 - 157,122,689 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,107,469 - 157,123,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,126,655 - 224,141,154 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,694,113 - 160,708,614 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14160,939,050 - 160,953,550 (+)NCBI
Celera4146,134,736 - 146,149,233 (+)NCBICelera
Cytogenetic Map4q42NCBI
C1rl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,662,303 - 4,670,638 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,663,643 - 4,670,454 (-)NCBIChiLan1.0ChiLan1.0
C1RL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,934,946 - 37,947,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,935,004 - 37,947,563 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,669,185 - 8,681,810 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,287,413 - 38,300,028 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,287,461 - 38,300,028 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,162,305 - 38,174,910 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,203,367 - 38,215,993 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,147,208 - 8,159,825 (-)NCBIUU_Cfam_GSD_1.0
C1rl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,028,277 - 102,038,797 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936709695,898 - 705,189 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C1RL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,627,313 - 63,640,057 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,623,398 - 63,640,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,054,584 - 66,079,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C1RL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,163,126 - 7,178,544 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,162,292 - 7,177,324 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,033,743 - 1,047,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C1rl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,687,500 - 3,692,872 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,686,866 - 3,693,293 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000050959   ⟹   ENSPPAP00000028115
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl127,139,094 - 7,155,104 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000050969   ⟹   ENSPPAP00000028125
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl127,139,831 - 7,155,196 (-)Ensembl
RefSeq Acc Id: XM_003820266   ⟹   XP_003820314
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,659,388 - 12,674,252 (-)NCBI
NHGRI_mPanPan11212,656,147 - 12,671,007 (-)NCBI
Mhudiblu_PPA_v0127,224,675 - 7,239,521 (-)NCBI
PanPan1.1127,139,831 - 7,155,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008973656   ⟹   XP_008971904
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,661,794 - 12,674,252 (-)NCBI
NHGRI_mPanPan11212,658,414 - 12,671,009 (-)NCBI
Mhudiblu_PPA_v0127,226,941 - 7,239,522 (-)NCBI
PanPan1.1127,142,236 - 7,155,196 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820314 (Get FASTA)   NCBI Sequence Viewer  
  XP_008971904 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028115.1
  ENSPPAP00000028125
  ENSPPAP00000028125.1
Reference Protein Sequences
RefSeq Acc Id: XP_003820314   ⟸   XM_003820266
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BEQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008971904   ⟸   XM_008973656
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000028115   ⟸   ENSPPAT00000050959
RefSeq Acc Id: ENSPPAP00000028125   ⟸   ENSPPAT00000050969
Protein Domains
CUB   Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037116 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050959.1 UniProtKB/TrEMBL
  ENSPPAT00000050969.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  2.60.120.290 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
InterPro CUB_dom UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report pps:100993128 UniProtKB/TrEMBL
NCBI Gene C1RL ENTREZGENE
PANTHER COMPLEMENT C1R SUBCOMPONENT-LIKE PROTEIN UniProtKB/TrEMBL
  COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED UniProtKB/TrEMBL
Pfam CUB UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE CUB UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART CUB UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF49854 UniProtKB/TrEMBL
  SSF50494 UniProtKB/TrEMBL
  SSF57535 UniProtKB/TrEMBL
UniProt A0A2R9BEP0_PANPA UniProtKB/TrEMBL
  A0A2R9BEQ0 ENTREZGENE, UniProtKB/TrEMBL