SPHKAP (SPHK1 interactor, AKAP domain containing) - Rat Genome Database

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Gene: SPHKAP (SPHK1 interactor, AKAP domain containing) Pan paniscus
Analyze
Symbol: SPHKAP
Name: SPHK1 interactor, AKAP domain containing
RGD ID: 11747318
Description: ENCODES a protein that exhibits protein kinase A binding (inferred); INVOLVED IN protein localization (inferred); ASSOCIATED WITH congestive heart failure (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (ortholog); Z disc (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A-kinase anchor protein SPHKAP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213130,592,990 - 130,795,095 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B115,218,846 - 115,420,826 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B234,028,622 - 234,229,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B234,028,622 - 234,229,874 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
mitochondrion  (ISO)
Z disc  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPHKAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213130,592,990 - 130,795,095 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B115,218,846 - 115,420,826 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B234,028,622 - 234,229,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B234,028,622 - 234,229,874 (-)Ensemblpanpan1.1panPan2
SPHKAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382227,979,955 - 228,181,687 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2227,979,955 - 228,181,687 (-)EnsemblGRCh38hg38GRCh38
GRCh372228,844,671 - 229,046,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,552,919 - 228,754,586 (-)NCBINCBI36Build 36hg18NCBI36
Celera2222,614,003 - 222,822,314 (-)NCBICelera
Cytogenetic Map2q36.3NCBI
HuRef2220,686,452 - 220,888,169 (-)NCBIHuRef
CHM1_12228,850,926 - 229,053,065 (-)NCBICHM1_1
T2T-CHM13v2.02228,462,353 - 228,663,979 (-)NCBIT2T-CHM13v2.0
Sphkap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39183,233,163 - 83,385,853 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl183,231,860 - 83,385,921 (-)EnsemblGRCm39 Ensembl
GRCm38183,255,442 - 83,408,411 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl183,254,139 - 83,408,200 (-)EnsemblGRCm38mm10GRCm38
MGSCv37183,252,356 - 83,404,775 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36183,134,466 - 83,287,190 (-)NCBIMGSCv36mm8
Celera183,319,854 - 83,471,360 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map142.73NCBI
Sphkap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8991,957,497 - 92,105,834 (-)NCBIGRCr8
mRatBN7.2984,509,383 - 84,657,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl984,510,964 - 84,657,559 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx992,939,568 - 93,087,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0998,068,049 - 98,216,175 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0996,457,425 - 96,609,490 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0989,050,405 - 89,195,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl989,050,381 - 89,195,273 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0988,791,639 - 88,936,765 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,576,572 - 82,766,985 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1982,766,883 - 82,907,353 (-)NCBI
Celera981,952,558 - 82,096,633 (-)NCBICelera
Cytogenetic Map9q35NCBI
Sphkap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554536,530,789 - 6,702,647 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554536,530,796 - 6,701,189 (+)NCBIChiLan1.0ChiLan1.0
SPHKAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12540,632,996 - 40,802,565 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2540,633,588 - 40,802,798 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2541,250,337 - 41,419,322 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02540,880,231 - 41,049,636 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2540,880,240 - 41,050,368 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12540,815,791 - 40,985,112 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02540,658,057 - 40,827,017 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02540,830,789 - 40,999,842 (-)NCBIUU_Cfam_GSD_1.0
Sphkap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303182,813,972 - 182,968,608 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365257,970,651 - 8,126,132 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365257,970,921 - 8,125,749 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPHKAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15129,308,627 - 129,460,960 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115129,308,621 - 129,461,142 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215143,188,649 - 143,341,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPHKAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110114,004,804 - 114,197,276 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10114,004,804 - 114,196,388 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604085,254,682 - 85,450,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sphkap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248432,131,961 - 2,248,093 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248432,133,924 - 2,285,162 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000030892   ⟹   ENSPPAP00000008257
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B234,028,622 - 234,229,874 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000030894   ⟹   ENSPPAP00000008259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B234,028,624 - 234,229,874 (-)Ensembl
RefSeq Acc Id: XM_008975308   ⟹   XP_008973556
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,094 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
Mhudiblu_PPA_v02B115,218,846 - 115,420,824 (-)NCBI
PanPan1.12B234,028,622 - 234,229,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008975309   ⟹   XP_008973557
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,094 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
Mhudiblu_PPA_v02B115,218,846 - 115,420,824 (-)NCBI
PanPan1.12B234,028,624 - 234,229,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034955311   ⟹   XP_034811202
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,095 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
Mhudiblu_PPA_v02B115,218,846 - 115,420,826 (-)NCBI
RefSeq Acc Id: XM_034955312   ⟹   XP_034811203
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,094 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
Mhudiblu_PPA_v02B115,218,846 - 115,420,824 (-)NCBI
RefSeq Acc Id: XM_057301524   ⟹   XP_057157507
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,093 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
RefSeq Acc Id: XM_057301525   ⟹   XP_057157508
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213130,592,990 - 130,795,092 (-)NCBI
NHGRI_mPanPan12B130,607,960 - 130,810,063 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008973556   ⟸   XM_008975308
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZZ69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008973557   ⟸   XM_008975309
- Peptide Label: isoform X5
- UniProtKB: A0A2R8ZTF4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034811202   ⟸   XM_034955311
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZZ69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811203   ⟸   XM_034955312
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZZ69 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000008259   ⟸   ENSPPAT00000030894
RefSeq Acc Id: ENSPPAP00000008257   ⟸   ENSPPAT00000030892
RefSeq Acc Id: XP_057157508   ⟸   XM_057301525
- Peptide Label: isoform X6
- UniProtKB: A0A2R8ZTF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157507   ⟸   XM_057301524
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZZ69 (UniProtKB/TrEMBL)
Protein Domains
A-kinase anchor 110kDa C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027369 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030892.1 UniProtKB/TrEMBL
  ENSPPAT00000030894.1 UniProtKB/TrEMBL
InterPro AKAP_110_C UniProtKB/TrEMBL
  SPHK1-interactor_AKAP_110 UniProtKB/TrEMBL
KEGG Report pps:100975918 UniProtKB/TrEMBL
NCBI Gene SPHKAP ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN SPHKAP UniProtKB/TrEMBL
  PTHR10226 UniProtKB/TrEMBL
Pfam AKAP_110 UniProtKB/TrEMBL
UniProt A0A2R8ZTF4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZZ69 ENTREZGENE, UniProtKB/TrEMBL