UNC13A (unc-13 homolog A) - Rat Genome Database

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Gene: UNC13A (unc-13 homolog A) Pan paniscus
Analyze
Symbol: UNC13A
Name: unc-13 homolog A
RGD ID: 11736397
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN amyloid-beta metabolic process (ortholog); dense core granule docking (ortholog); innervation (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autistic disorder (ortholog); cerebellar ataxia (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); excitatory synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,471,816 - 22,558,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,478,384 - 21,565,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,088,654 - 17,175,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,063,260 - 18,150,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UNC13A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,471,816 - 22,558,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,478,384 - 21,565,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,088,654 - 17,175,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,063,260 - 18,150,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensemblpanpan1.1panPan2
UNC13A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,601,336 - 17,688,354 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,601,336 - 17,688,365 (-)EnsemblGRCh38hg38GRCh38
GRCh371917,712,145 - 17,799,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,573,137 - 17,660,401 (-)NCBINCBI36Build 36hg18NCBI36
Celera1917,613,819 - 17,700,754 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,276,161 - 17,362,803 (-)NCBIHuRef
CHM1_11917,711,616 - 17,798,549 (-)NCBICHM1_1
T2T-CHM13v2.01917,735,579 - 17,822,489 (-)NCBIT2T-CHM13v2.0
Unc13a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,079,356 - 72,124,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,077,061 - 72,124,401 (-)EnsemblGRCm39 Ensembl
GRCm38871,624,125 - 71,671,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,624,417 - 71,671,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37874,150,611 - 74,195,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36874,558,412 - 74,600,636 (-)NCBIMGSCv36mm8
Celera874,140,993 - 74,186,237 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.43NCBI
Unc13a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,367,891 - 18,415,808 (-)NCBIGRCr8
mRatBN7.21618,333,910 - 18,381,813 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,336,229 - 18,381,872 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,384,673 - 18,432,402 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,516,945 - 19,565,015 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,437,617 - 18,485,341 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,056,398 - 20,103,951 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,056,765 - 20,097,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,917,585 - 19,964,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,827,405 - 18,872,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,827,402 - 18,872,453 (-)NCBI
Celera1618,539,912 - 18,584,310 (-)NCBICelera
Cytogenetic Map16p14NCBI
Unc13a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955524725,353 - 769,745 (+)NCBIChiLan1.0ChiLan1.0
UNC13A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,179,275 - 45,237,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,188,750 - 45,238,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,091,418 - 45,152,586 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,664,551 - 45,729,225 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,664,566 - 45,726,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,900,707 - 44,962,114 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,311,011 - 45,375,605 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,586,777 - 45,648,193 (+)NCBIUU_Cfam_GSD_1.0
Unc13a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,763,514 - 203,824,246 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365963,312,788 - 3,368,916 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365963,311,358 - 3,370,833 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1260,057,926 - 60,130,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,626,729 - 59,665,341 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC13A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,082,703 - 16,167,165 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,084,168 - 16,154,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc13a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908418,248 - 464,203 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000037320   ⟹   ENSPPAP00000014633
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000037325   ⟹   ENSPPAP00000014638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000037327   ⟹   ENSPPAP00000014640
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000037330   ⟹   ENSPPAP00000014643
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensembl
RefSeq Acc Id: XM_034945489   ⟹   XP_034801380
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,471,816 - 22,558,672 (-)NCBI
NHGRI_mPanPan11921,478,384 - 21,565,289 (-)NCBI
Mhudiblu_PPA_v01917,092,243 - 17,175,559 (-)NCBI
RefSeq Acc Id: XM_034945495   ⟹   XP_034801386
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,471,816 - 22,558,671 (-)NCBI
NHGRI_mPanPan11921,478,384 - 21,565,288 (-)NCBI
Mhudiblu_PPA_v01917,092,243 - 17,175,558 (-)NCBI
RefSeq Acc Id: XM_055103782   ⟹   XP_054959757
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,471,816 - 22,558,671 (-)NCBI
NHGRI_mPanPan11921,478,384 - 21,565,288 (-)NCBI
RefSeq Acc Id: XM_055103783   ⟹   XP_054959758
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22022,471,816 - 22,558,671 (-)NCBI
NHGRI_mPanPan11921,478,384 - 21,565,289 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034801380   ⟸   XM_034945489
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034801386   ⟸   XM_034945495
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000014643   ⟸   ENSPPAT00000037330
RefSeq Acc Id: ENSPPAP00000014638   ⟸   ENSPPAT00000037325
RefSeq Acc Id: ENSPPAP00000014640   ⟸   ENSPPAT00000037327
RefSeq Acc Id: ENSPPAP00000014633   ⟸   ENSPPAT00000037320
RefSeq Acc Id: XP_054959758   ⟸   XM_055103783
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054959757   ⟸   XM_055103782
- Peptide Label: isoform X1
Protein Domains
C2   MHD1   MHD2   Phorbol-ester/DAG-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030394 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037320.1 UniProtKB/TrEMBL
  ENSPPAT00000037325.1 UniProtKB/TrEMBL
  ENSPPAT00000037327.1 UniProtKB/TrEMBL
  ENSPPAT00000037330.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  MUN_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Unc-13 UniProtKB/TrEMBL
  Unc-13_C2B UniProtKB/TrEMBL
NCBI Gene UNC13A ENTREZGENE
PANTHER PTHR10480 UniProtKB/TrEMBL
  PTHR10480:SF1 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  DUF1041 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART DUF1041 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A2R9ABK0_PANPA UniProtKB/TrEMBL
  A0A2R9AGG9_PANPA UniProtKB/TrEMBL
  A0A2R9AGH5_PANPA UniProtKB/TrEMBL
  A0A2R9AGI1_PANPA UniProtKB/TrEMBL