NKX2-5 (NK2 homeobox 5) - Rat Genome Database

Name: NKX2-5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NKX2-5 (NK2 homeobox 5) Pan paniscus

Analyze

Symbol:

NKX2-5

Name:

NK2 homeobox 5

RGD ID:

11735052

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN adult heart development (ortholog); apoptotic process (ortholog); apoptotic process involved in heart morphogenesis (ortholog); ASSOCIATED WITH aortic valve disease 2 (ortholog); atrial fibrillation (ortholog); atrial heart septal defect (ortholog); FOUND IN Nkx-2.5 complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

homeobox protein Nkx-2.5

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NKX2-5 (NK2 homeobox 5)	NCBI	Ortholog
Mus musculus (house mouse):	Nkx2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nkx2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nkx2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NKX2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nkx2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NKX2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NKX2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nkx2-5 (NK2 homeobox 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	168,367,607 - 168,372,490 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	166,507,149 - 166,512,032 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	168,584,197 - 168,589,406 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	175,492,288 - 175,495,514 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	175,492,288 - 175,495,514 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aortic valve disease 2 (ISO)

atrial fibrillation (ISO)

atrial heart septal defect (ISO)

atrial heart septal defect 7 (ISO)

Atrial Septal Defect with Atrioventricular Conduction Defects (ISO)

atrioventricular block (ISO)

atrioventricular septal defect (ISO)

Cardiac Conduction Defect (ISO)

Cardiomegaly (ISO)

Cardiovascular Abnormalities (ISO)

Common Ventricle (ISO)

congenital heart disease (ISO)

congenital nongoitrous hypothyroidism 5 (ISO)

Conotruncal Cardiac Defects (ISO)

dilated cardiomyopathy (ISO)

genetic disease (ISO)

heart septal defect (ISO)

hypertrophic cardiomyopathy (ISO)

hypoplastic left heart syndrome (ISO)

Hypoplastic Left Heart Syndrome 2 (ISO)

lissencephaly 3 (ISO)

long QT syndrome (ISO)

myotonic disease (ISO)

pulmonary fibrosis (ISO)

second-degree atrioventricular block (ISO)

Splenic Hypoplasia (ISO)

Stroke (ISO)

tetralogy of Fallot (ISO)

Ventricular Fibrillation (ISO)

ventricular septal defect (ISO)

Ventricular Septal Defect 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult heart development (IEA,ISO)

apoptotic process (IEA,ISO)

apoptotic process involved in heart morphogenesis (IEA,ISO)

atrial cardiac muscle tissue development (IEA)

atrial septum morphogenesis (IEA)

atrioventricular node cell development (IEA,ISO)

atrioventricular node cell fate commitment (IEA,ISO)

atrioventricular node development (IEA)

bundle of His development (IEA,ISO)

cardiac conduction system development (IEA,ISO)

cardiac muscle cell development (IEA)

cardiac muscle cell differentiation (IEA,ISO)

cardiac muscle cell proliferation (IEA,ISO)

cardiac muscle contraction (IEA,ISO)

cardiac muscle tissue development (IEA,ISO)

cardiac muscle tissue morphogenesis (IEA)

cardiac septum morphogenesis (IEA)

cardiac ventricle formation (IEA,ISO)

cardiac ventricle morphogenesis (IEA,ISO)

cell differentiation (IEA)

cell population proliferation (IEA,ISO)

cellular response to growth factor stimulus (ISO)

cellular response to hydrogen peroxide (ISO)

embryonic heart tube development (IEA,ISO)

embryonic heart tube left/right pattern formation (IEA,ISO)

epithelial cell apoptotic process (IEA,ISO)

epithelial cell differentiation (IEA,ISO)

epithelial cell proliferation (IEA,ISO)

heart contraction (IEA,ISO)

heart development (IEA,ISO)

heart looping (IEA,ISO)

heart morphogenesis (IEA,ISO)

heart trabecula formation (IEA,ISO)

hemopoiesis (IEA,ISO)

negative regulation of canonical Wnt signaling pathway (IEA)

negative regulation of cardiac muscle cell apoptotic process (IEA)

negative regulation of epithelial cell apoptotic process (IEA,ISO)

negative regulation of myotube differentiation (IEA)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

outflow tract morphogenesis (IEA,ISO)

outflow tract septum morphogenesis (IEA)

pharyngeal system development (IEA,ISO)

positive regulation of cardioblast differentiation (IEA)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of epithelial cell proliferation (IEA,ISO)

positive regulation of gene expression (IEA)

positive regulation of heart contraction (IEA)

positive regulation of neuron differentiation (IEA)

positive regulation of sodium ion transport (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription initiation by RNA polymerase II (IEA)

proepicardium development (IEA,ISO)

pulmonary myocardium development (IEA,ISO)

Purkinje myocyte differentiation (IEA,ISO)

regulation of cardiac conduction (IEA)

regulation of cardiac muscle cell proliferation (IEA,ISO)

regulation of cardiac muscle contraction (IEA)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IEA,ISO)

response to estradiol (ISO)

right ventricular cardiac muscle tissue morphogenesis (IEA)

septum secundum development (IEA)

spleen development (IEA,ISO)

thyroid gland development (IEA)

transcription by RNA polymerase II (IEA,ISO)

vasculogenesis (IEA,ISO)

ventricular cardiac myofibril assembly (IEA,ISO)

ventricular septum morphogenesis (IEA)

ventricular trabecula myocardium morphogenesis (IEA,ISO)

Cellular Component

cytoplasm (IEA)

Nkx-2.5 complex (IEA,ISO)

nucleus (IEA)

protein-containing complex (IEA)

protein-DNA complex (IEA)

RNA polymerase II transcription regulator complex (IEA)

transcription regulator complex (IEA)

Molecular Function

chromatin binding (IEA)

DNA binding (IEA)

DNA-binding transcription activator activity (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

histone deacetylase binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

protein homodimerization activity (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA)

sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (IEA)

transcription cis-regulatory region binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NKX2-5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	168,367,607 - 168,372,490 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	166,507,149 - 166,512,032 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	168,584,197 - 168,589,406 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	175,492,288 - 175,495,514 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	175,492,288 - 175,495,514 (-)	Ensembl	panpan1.1		panPan2

NKX2-5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	173,232,109 - 173,235,206 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	173,232,109 - 173,235,311 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	172,659,112 - 172,662,209 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	172,591,744 - 172,594,868 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	168,692,473 - 168,695,681 (-)	NCBI		Celera
Cytogenetic Map	5	q35.1	NCBI
HuRef	5	167,754,405 - 167,757,613 (-)	NCBI		HuRef
CHM1_1	5	172,091,589 - 172,094,797 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	173,772,181 - 173,775,278 (-)	NCBI		T2T-CHM13v2.0

Nkx2-5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	27,057,638 - 27,063,962 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	27,057,638 - 27,063,983 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	26,838,664 - 26,844,988 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	26,838,664 - 26,845,009 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	26,975,610 - 26,978,510 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	26,566,254 - 26,569,154 (-)	NCBI		MGSCv36	mm8
Celera	17	27,375,289 - 27,378,187 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	13.6	NCBI

Nkx2-5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	16,844,888 - 16,851,458 (+)	NCBI		GRCr8
mRatBN7.2	10	16,340,428 - 16,347,004 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	16,344,159 - 16,346,934 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	21,093,028 - 21,095,888 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	20,581,977 - 20,584,837 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	16,071,642 - 16,074,502 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	16,635,989 - 16,638,758 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	16,635,989 - 16,638,764 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	16,520,570 - 16,527,836 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	16,606,183 - 16,608,952 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	16,607,231 - 16,610,001 (+)	NCBI
Celera	10	16,004,548 - 16,007,317 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Nkx2-5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	25,832,683 - 25,836,840 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	25,833,649 - 25,836,673 (-)	NCBI	ChiLan1.0	ChiLan1.0

NKX2-5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	39,240,755 - 39,254,585 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	39,244,286 - 39,247,592 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	39,189,667 - 39,192,973 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	39,612,560 - 39,618,296 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	39,614,913 - 39,618,296 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	39,432,539 - 39,435,856 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	39,621,539 - 39,624,869 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	40,130,495 - 40,133,809 (+)	NCBI		UU_Cfam_GSD_1.0

Nkx2-5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	93,683,325 - 93,686,308 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936609	2,406,004 - 2,409,046 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936609	2,406,004 - 2,408,980 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NKX2-5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	51,086,011 - 51,089,162 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	51,086,014 - 51,089,165 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	55,400,567 - 55,403,626 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NKX2-5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	75,391,833 - 75,399,003 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	75,391,847 - 75,395,205 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	3,212,995 - 3,216,184 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nkx2-5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	16,881,191 - 16,884,210 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	16,881,189 - 16,884,245 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003814003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008966606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008966607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055112877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000038549 ⟹ ENSPPAP00000015856

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	175,492,288 - 175,495,514 (-)	Ensembl

RefSeq Acc Id:

XM_003814003 ⟹ XP_003814051

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	168,367,607 - 168,372,490 (-)	NCBI
NHGRI_mPanPan1	5	166,507,149 - 166,512,032 (-)	NCBI
Mhudiblu_PPA_v0	5	168,584,197 - 168,589,406 (-)	NCBI
PanPan1.1	5	175,492,288 - 175,495,514 (-)	NCBI

Sequence:

show sequence

CTGCTCATCGCTCCTGTCATCGAGGCCCCTGGCCCAATGGCAGGCTGAGTCCCCCTCCTCTGGC
CTGGTCCCGCCTCTCCTGCCCCTTGTGCTCAGCGCTACCTGCTGCCCGGACACATCAAGAGCTG
GCCGGCGGGTGCGCGGGCGGGCGGCGGCACCATGCAGGGAAGCTGCCAGGGGCCGTGGGCAGCG
CCGCTTTCTGCCGCCCACCTGGCGCTGTGAGACTGGCGCTGCCACCATGTTCCCCAGCCCTGCT
CTCACGCCCACGCCCTTCTCAGTCAAAGACATCCTAAACCTGGAGCAGCAGCAGCGCAGCCTGG
CTGCCGCCGGAGAGCTCTCTGCCCGCCTGGAGGCGACCCTGGCGCCCTCCTCCTGCATGCTGGC
CGCCTTCAAGCCAGAGGCCTACGCTGGGCCCGAGGCGGCTGCGCCGGGCCTCCCAGAGCTGCGC
GCAGAGCTGGGCCGCGCGCCTTCACCGGCCAAGTGTGCGTCTGCCTTTCCCGCCGCCCCCGCCT
TCTATCCACGTGCCTACAGCGACCCCGACCCAGCCAAGGACCCTAGAGCCGAAAAGAAAGAGCT
GTGCGCGCTGCAGAAGGCGGTGGAGCTGGAGAAGACAGAGGCGGACAACGCGGAGCGGCCCCGG
GCGCGACGGCGGAGGAAGCCGCGGGTGCTCTTCTCGCAGGCGCAGGTCTATGAGCTGGAGCGGC
GCTTCAAGCAGCAGCGGTACCTGTCGGCCCCCGAACGCGACCAGCTGGCCAGCGTGCTGAAACT
CACGTCCACGCAGGTCAAGATCTGGTTCCAGAACCGGCGCTACAAGTGCAAGCGGCAGCGGCAG
GACCAGACTCTGGAGCTGGTGGGGCTGCCCCCGCCGCCGCCGCCGCCGCCTGCCCGCAGGATCG
CGGTGCCAGTGCTGGTGCGCGATGGCAAGCCATGCCTAGGGGACTCGGCGCCCTACGCGCCTGC
CTACGGCGTGGGCCTCAATCCCTACGGTTATAACGCCTACCCCGCCTATCCGGGTTATGGCGGC
GCGGCCTGCAGCCCTGGCTACAGCTGCACTGCGGCTTACCCCGCCGGGCCTTCCCCAGCGCAGC
CGGCCACTGCCGCCGCCAACAACAACTTCGTGAACTTCGGCGTCGGGGACTTGAATGCGGTTCA
GAGCCCCGGGATTCCGCAGAGCAACTCGGGAGTGTCCACGCTGCATGGTATCCGAGCCTGGTAG
GGAAGGGACCCGCGTGGCGCGACCCTGACCGATCCCACCTCAACAGCTCCCCGACTCTCGGGGG
GAGAAGGGGCTCCCAACATGACCCTGAGTCCCCTGGATTTTGCATTCACTCCTGCGGAGACCTA
GGAACTTTTTCTGTCCCACGCGCGTTTGTTCTTGCGCACGGGAGAGTTTGTGGCGGCGATTATG
CAGCGTGCAATGAGTGATCCTGCAGCCTGGTGTCTTAGCTGTCCCCCCAGGAGTGCCCTCCGAG
AGTCCATGGGCACCCCCGGTTGGAACTGGGACTGAGCTCGGGCACGCAGGGCCTGAGATCTGGC
CGCCCATTCTGCGAGCCAGGGCCGGGCGCCCGGGCCTTTGCTATCTCGCCGTCGCCCGCCCACG
CACCCACCCGTATTTATGTTTTTACCTATTGCTGTAAGAAATGAGGATCCCCTTCCCATTAAAG
AGAGTGCGTTGA

hide sequence

RefSeq Acc Id:

XM_055112877 ⟹ XP_054968852

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	168,368,523 - 168,372,490 (-)	NCBI
NHGRI_mPanPan1	5	166,508,065 - 166,512,032 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003814051	(Get FASTA)	NCBI Sequence Viewer
	XP_054968852	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000015856
	ENSPPAP00000015856.1

RefSeq Acc Id:	XP_003814051 ⟸ XM_003814003
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AEW5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAP GLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEAD NAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYK CKRQRQDQTLELVGLPPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPA YPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLH GIRAW hide sequence

RefSeq Acc Id:

ENSPPAP00000015856 ⟸ ENSPPAT00000038549

RefSeq Acc Id:	XP_054968852 ⟸ XM_055112877
- Peptide Label:	isoform X2

Protein Domains

Homeobox

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000031047	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000038549.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
KEGG Report	pps:100982957	UniProtKB/TrEMBL
NCBI Gene	NKX2-5	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN NKX	UniProtKB/TrEMBL
	PTHR24340:SF28	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A2R9AEW5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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