CDK3 (cyclin dependent kinase 3) - Rat Genome Database

Name: CDK3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: CDK3 (cyclin dependent kinase 3) Pan paniscus

Analyze

Symbol:

CDK3

Name:

cyclin dependent kinase 3

RGD ID:

11711814

Description:

ENCODES a protein that exhibits ATP binding (inferred); cyclin binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); INVOLVED IN DNA damage response (ortholog); FOUND IN cyclin-dependent protein kinase holoenzyme complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cyclin-dependent kinase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	92,041,771 - 92,047,209 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,866,778 - 96,872,220 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,947,125 - 69,952,567 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	75,498,018 - 75,503,448 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	75,498,134 - 75,503,448 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA,ISO)

G0 to G1 transition (IEA)

G1/S transition of mitotic cell cycle (IEA)

negative regulation of Notch signaling pathway (IEA)

regulation of G2/M transition of mitotic cell cycle (IEA)

regulation of gene expression (IEA)

signal transduction (IEA)

Cellular Component

cyclin-dependent protein kinase holoenzyme complex (IEA,ISO)

cytoplasm (IEA)

nucleus (IEA)

Molecular Function

ATP binding (IEA)

cyclin binding (IEA)

cyclin-dependent protein serine/threonine kinase activity (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CDK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	92,041,771 - 92,047,209 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,866,778 - 96,872,220 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,947,125 - 69,952,567 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	75,498,018 - 75,503,448 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	75,498,134 - 75,503,448 (+)	Ensembl	panpan1.1		panPan2

CDK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	76,000,855 - 76,005,998 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	76,000,855 - 76,005,999 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	73,996,936 - 74,002,079 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	71,509,014 - 71,513,251 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	71,509,013 - 71,513,251	NCBI
Celera	17	70,587,026 - 70,592,127 (+)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	69,422,590 - 69,427,691 (+)	NCBI		HuRef
CHM1_1	17	74,061,816 - 74,066,916 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	76,893,983 - 76,899,134 (+)	NCBI		T2T-CHM13v2.0

Cdk3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	116,106,828 - 116,111,113 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	116,106,829 - 116,111,113 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	116,216,002 - 116,220,287 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	116,216,003 - 116,220,287 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	116,077,316 - 116,081,601 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	116,032,630 - 116,036,375 (+)	NCBI		MGSCv36	mm8
Celera	11	127,980,674 - 127,984,962 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	81.02	NCBI

Cdk3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	6,247,146 - 6,252,043 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	6,247,146 - 6,252,083 (-)	NCBI	ChiLan1.0	ChiLan1.0

CDK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	4,631,025 - 4,635,122 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	4,631,506 - 4,635,605 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,311,517 - 5,315,688 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,301,376 - 5,305,553 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	5,301,857 - 5,304,972 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	5,341,280 - 5,345,458 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	5,450,722 - 5,454,885 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	5,511,230 - 5,515,408 (-)	NCBI		UU_Cfam_GSD_1.0

Cdk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	5,247,221 - 5,252,799 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	1,160,268 - 1,169,103 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	1,159,644 - 1,164,735 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	5,426,762 - 5,430,999 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	5,426,751 - 5,430,974 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	5,382,041 - 5,386,265 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	45,681,006 - 45,686,958 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	16,429,936 - 16,435,895 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	5,900,971 - 5,904,756 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	5,900,484 - 5,905,460 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008965813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034942918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063599417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000054222 ⟹ ENSPPAP00000031358

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	75,498,134 - 75,503,448 (+)	Ensembl

RefSeq Acc Id:

XM_008965813 ⟹ XP_008964061

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	92,041,771 - 92,047,209 (+)	NCBI
NHGRI_mPanPan1	17	96,866,778 - 96,872,220 (+)	NCBI
Mhudiblu_PPA_v0	17	69,947,125 - 69,952,567 (+)	NCBI
PanPan1.1	17	75,498,018 - 75,503,448 (+)	NCBI

Sequence:

show sequence

AGTGTGCTCGTGGTGCAGCGCCAGCGGGGGCCAGGAGGGGGAGCTGCAACCCAGGCTGTGGGCA
GCAGCCTCTCAGGGCTTCTGGTGAATTCTGGGCCTGAGGCCTCAGGGCAGCTCTGTGGCCATGG
ATATGTTCCAGAAGGTAGAGAAGATCGGAGAGGGCACCTATGGGGTGGTGTACAAGGCCAAGAA
CAGGGAGACAGGGCAGCTGGTGGCCCTGAAGAAGATCAGACTGGATTTGGAGATGGAGGGGGTC
CCAAGCACTGCCATCAGGGAGATCTCGCTGCTCAAGGAACTGAAGCACCCCAACATCGTCCGAC
TGCTGGACGTGGTGCACAACGAGAGGAAGCTCTATCTGGTGTTTGAGTTCCTCAGCCAGGACCT
GAAGAAGTACATGGACTCCACCCCAGGCTCAGAGCTCCCCCTGCACCTCATCAAGAGCTACCTC
TTCCAGCTGCTGCAGGGGGTGAGTTTCTGCCACTCACATCGGGTCATCCACCGAGACCTGAAGC
CCCAGAACCTGCTCATCAATGAGTTGGGTGCCATCAAGCTGGCTGACTTCGGCCTGGCTCGCGC
CTTTGGGGTGCCCCTGCGCACCTACACCCATGAGGTGGTGACACTGTGGTATCGCGCCCCCGAG
ATTCTCTTGGGCAGCAAGTTCTATACCACAGCTGTGGATATCTGGAGCATTGGTTGCATCTTTG
CAGAGATGGTGACTCGAAAAGCCCTGTTTCCTGGTGACTCTGAGATTGACCAGCTCTTTCGTAT
CTTTCGTATGCTGGGGACACCCAGCGAAGACACATGGCCCGGGGTCACCCAGCTGCCTGACTAT
AAGGGCAGCTTCCCTAAGTGGACCAGGAAGGGACTGGAAGAGATTGTGCCCAATCTGGAGCCAG
AAGGCAGGGACCTGCTCATGCAACTCCTGCAGTATGACCCCAGCCAGCGGATCACAGCCAAGAC
TGCCCTGGCCCACCCGTACTTCTCATCCCCTGAGCCCTCCCCAGCTGCCCGCCAGTATGTGCTG
CAGCGATTCCACCATTGAGAATGTCAGGGCCACACTCAGATCCTTTCTCGAGCAGCTGCTGCCC
CAGCTGCCTCCTACCCATTGCCAAGAGAGGATGCATCTGGGGAGAGCAAAGCACTAAGGAATTT
AGCATCAGCCTGCAGAGGGCTGAGTCTGGGTTAGTCCTGCCCGCAGGTTAGCGAGATCCTGTGT
TGTTTTTTGGGTTGGATGGTGCCGTTTCAAAATAGAGGCACAGATGCTCCATGCACGAGGGGTC
CCTGGGCACTGGAACAAGTGCCAAGTTGAAGGCAGGGGGCCTGCCAGAGCTGGGTGTGGGTATT
CAGGCCCTCACCTGCCCCGCCTGCAGGGCCAGACCCTGAGGAAAGGGCGCCCCCTGCTGGTCTT
TTTGGATTTAAAAAATGTTTGGGGAAGAGTTGAGTTCCAGTTCAGAGTCCCAAGTTAAACAGGA
GGGAGTGAGGGAGAGGACAGAGGGCGTTCCCCGGATCCCAGGAGAGCTGGGCTATGACTGCAAT
AAGGAGTTGTTCCTTCACCTGAGATGTGCTTCTTTTGGTTCATTTCTGGCTTGACAACAAGAAA
TAAACGTGGTATGTTCCTGAG

hide sequence

RefSeq Acc Id:

XM_063599417 ⟹ XP_063455487

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	92,041,935 - 92,047,209 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008964061	(Get FASTA)	NCBI Sequence Viewer
	XP_063455487	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000031358
	ENSPPAP00000031358.1

RefSeq Acc Id:	XP_008964061 ⟸ XM_008965813
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BSE8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIV RLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDL KPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCI FAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLE PEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFHH hide sequence

RefSeq Acc Id:

ENSPPAP00000031358 ⟸ ENSPPAT00000054222

RefSeq Acc Id:	XP_063455487 ⟸ XM_063599417
- Peptide Label:	isoform X1

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000038619	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000054222.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	pps:100985860	UniProtKB/TrEMBL
NCBI Gene	CDK3	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/TrEMBL
	CYCLIN-DEPENDENT KINASE 3	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9BSE8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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