GNG8 (G protein subunit gamma 8) - Rat Genome Database

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Gene: GNG8 (G protein subunit gamma 8) Pan paniscus
Analyze
Symbol: GNG8
Name: G protein subunit gamma 8
RGD ID: 11706071
Description: ENCODES a protein that exhibits G-protein beta-subunit binding (inferred); INVOLVED IN cellular response to pheromone (ortholog); nervous system development (ortholog); nose development (ortholog); ASSOCIATED WITH liver disease (ortholog); long QT syndrome 1 (ortholog); Walker-Warburg syndrome (ortholog); FOUND IN heterotrimeric G-protein complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,783,979 - 52,795,059 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,654,750 - 54,668,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,626,498 - 43,637,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,155,081 - 52,157,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,155,081 - 52,156,410 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GNG8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,783,979 - 52,795,059 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,654,750 - 54,668,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,626,498 - 43,637,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,155,081 - 52,157,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,155,081 - 52,156,410 (-)Ensemblpanpan1.1panPan2
GNG8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,633,953 - 46,639,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,633,953 - 46,636,541 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,137,210 - 47,139,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,829,173 - 51,829,779 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,829,172 - 51,829,779NCBI
Celera1943,940,858 - 43,941,464 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,562,343 - 43,562,949 (-)NCBIHuRef
CHM1_11947,139,178 - 47,139,784 (-)NCBICHM1_1
T2T-CHM13v2.01949,459,562 - 49,464,865 (-)NCBIT2T-CHM13v2.0
Gng8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,625,687 - 16,629,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,625,711 - 16,629,361 (+)EnsemblGRCm39 Ensembl
GRCm38716,891,737 - 16,895,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,891,786 - 16,895,436 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,477,135 - 17,480,784 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36716,050,308 - 16,053,957 (+)NCBIMGSCv36mm8
Celera714,098,204 - 14,101,853 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Gng8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,692,609 - 86,696,463 (+)NCBIGRCr8
mRatBN7.2177,564,512 - 77,568,371 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,564,515 - 77,568,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,946,593 - 82,948,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,510,638 - 91,512,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,701,683 - 84,703,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,818,360 - 78,822,224 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,818,404 - 78,822,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0180,065,774 - 80,069,629 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,221,378 - 77,223,313 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,299,411 - 77,301,424 (+)NCBI
Celera172,050,870 - 72,053,464 (+)NCBICelera
Cytogenetic Map1q21NCBI
Gng8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574697,254 - 699,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574697,254 - 699,282 (-)NCBIChiLan1.0ChiLan1.0
GNG8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,266,884 - 109,268,515 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,268,056 - 109,268,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,744,363 - 108,747,819 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,791,074 - 109,794,528 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,794,069 - 109,794,466 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,468,171 - 109,471,624 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,102,370 - 109,105,802 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,971,075 - 109,974,533 (+)NCBIUU_Cfam_GSD_1.0
Gng8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,877,671 - 18,881,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664495,810 - 497,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664495,823 - 496,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNG8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,534,662 - 52,536,414 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,534,952 - 52,541,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,854,442 - 47,861,734 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNG8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,989,915 - 39,995,714 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,989,903 - 39,990,910 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,701,879 - 19,707,655 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gng8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,937,339 - 6,940,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,937,309 - 6,941,101 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000043481   ⟹   ENSPPAP00000020685
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1952,155,081 - 52,156,410 (-)Ensembl
RefSeq Acc Id: XM_008970686   ⟹   XP_008968934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,783,979 - 52,785,918 (-)NCBI
NHGRI_mPanPan11954,654,750 - 54,656,742 (-)NCBI
Mhudiblu_PPA_v01943,626,498 - 43,628,102 (-)NCBI
PanPan1.11952,155,081 - 52,156,410 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024926706   ⟹   XP_024782474
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,783,979 - 52,786,030 (-)NCBI
NHGRI_mPanPan11954,654,750 - 54,656,866 (-)NCBI
Mhudiblu_PPA_v01943,626,498 - 43,628,561 (-)NCBI
PanPan1.11952,155,081 - 52,157,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034945999   ⟹   XP_034801890
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,783,979 - 52,795,027 (-)NCBI
NHGRI_mPanPan11954,654,750 - 54,668,068 (-)NCBI
Mhudiblu_PPA_v01943,626,498 - 43,637,560 (-)NCBI
RefSeq Acc Id: XM_034946000   ⟹   XP_034801891
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,783,979 - 52,795,059 (-)NCBI
NHGRI_mPanPan11954,654,750 - 54,668,068 (-)NCBI
Mhudiblu_PPA_v01943,626,498 - 43,637,618 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008968934 (Get FASTA)   NCBI Sequence Viewer  
  XP_024782474 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801890 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801891 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020685
  ENSPPAP00000020685.1
RefSeq Acc Id: XP_008968934   ⟸   XM_008970686
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024782474   ⟸   XM_024926706
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AXY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034801891   ⟸   XM_034946000
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AXY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034801890   ⟸   XM_034945999
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AXY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000020685   ⟸   ENSPPAT00000043481
Protein Domains
G protein gamma


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033557 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043481.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.260.10 UniProtKB/TrEMBL
InterPro G-protein_gamma-like_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  Gprotein-gamma UniProtKB/TrEMBL
NCBI Gene GNG8 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-8 UniProtKB/TrEMBL
  PTHR13809 UniProtKB/TrEMBL
Pfam G-gamma UniProtKB/TrEMBL
PRINTS GPROTEING UniProtKB/TrEMBL
PROSITE G_PROTEIN_GAMMA UniProtKB/TrEMBL
SMART G_gamma UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
Superfamily-SCOP SSF48670 UniProtKB/TrEMBL
UniProt A0A2R9AXY4 ENTREZGENE, UniProtKB/TrEMBL