KPNB1 (karyopherin subunit beta 1) - Rat Genome Database

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Gene: KPNB1 (karyopherin subunit beta 1) Pan paniscus
Analyze
Symbol: KPNB1
Name: karyopherin subunit beta 1
RGD ID: 11694740
Description: ENCODES a protein that exhibits kinesin binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN protein import into nucleus (ortholog); ribosomal protein import into nucleus (ortholog); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); ovarian carcinoma (ortholog); FOUND IN cytoplasm (ortholog); NLS-dependent protein nuclear import complex (ortholog); nuclear pore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin subunit beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,417,441 - 17,453,002 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,382,919 - 19,418,880 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,852,424 - 9,887,111 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,035,738 - 10,068,401 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1710,035,732 - 10,068,913 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KPNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,417,441 - 17,453,002 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,382,919 - 19,418,880 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,852,424 - 9,887,111 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,035,738 - 10,068,401 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1710,035,732 - 10,068,913 (-)Ensemblpanpan1.1panPan2
KPNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,649,919 - 47,685,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,649,476 - 47,685,505 (+)EnsemblGRCh38hg38GRCh38
GRCh371745,727,285 - 45,762,871 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,082,274 - 43,116,003 (+)NCBINCBI36Build 36hg18NCBI36
Build 341743,082,273 - 43,116,003NCBI
Celera1742,179,952 - 42,213,682 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,096,264 - 41,130,080 (+)NCBIHuRef
CHM1_11745,792,168 - 45,825,949 (+)NCBICHM1_1
T2T-CHM13v2.01748,511,703 - 48,547,295 (+)NCBIT2T-CHM13v2.0
Kpnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,050,536 - 97,078,718 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,050,540 - 97,078,707 (-)EnsemblGRCm39 Ensembl
GRCm381197,159,710 - 97,187,892 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,159,714 - 97,187,881 (-)EnsemblGRCm38mm10GRCm38
MGSCv371197,021,024 - 97,049,206 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,975,800 - 97,003,982 (-)NCBIMGSCv36mm8
Celera11106,812,630 - 106,840,820 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.95NCBI
Kpnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,642,082 - 82,670,856 (-)NCBIGRCr8
mRatBN7.21082,145,662 - 82,174,437 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1082,145,420 - 82,174,605 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1087,094,110 - 87,122,899 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01086,592,172 - 86,620,969 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,984,776 - 82,013,559 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01085,096,517 - 85,124,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,093,841 - 85,124,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,886,484 - 84,914,805 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,882,382 - 85,910,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11085,896,751 - 85,925,175 (-)NCBI
Celera1080,906,145 - 80,931,812 (-)NCBICelera
Cytogenetic Map10q31NCBI
Kpnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,365,476 - 13,398,491 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,365,881 - 13,398,491 (-)NCBIChiLan1.0ChiLan1.0
KPNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,004,191 - 24,031,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,003,968 - 24,028,531 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,470,348 - 23,497,535 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0924,796,218 - 24,823,411 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl924,795,998 - 24,821,055 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,566,722 - 23,593,892 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0923,827,962 - 23,855,184 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0923,954,771 - 23,981,965 (+)NCBIUU_Cfam_GSD_1.0
Kpnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,439,655 - 23,471,619 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,603,498 - 13,635,682 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,603,520 - 13,635,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KPNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,916,164 - 23,944,588 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,915,783 - 23,945,407 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21223,785,821 - 23,813,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KPNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,047,473 - 68,083,290 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,047,491 - 68,084,778 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,091,438 - 39,128,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kpnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,371,749 - 4,403,217 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,372,014 - 4,403,061 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003827476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000034007   ⟹   ENSPPAP00000011352
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1710,035,732 - 10,068,913 (-)Ensembl
RefSeq Acc Id: XM_003827476   ⟹   XP_003827524
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,417,441 - 17,453,002 (-)NCBI
NHGRI_mPanPan11719,382,919 - 19,418,880 (-)NCBI
Mhudiblu_PPA_v0179,852,424 - 9,887,111 (-)NCBI
PanPan1.11710,035,738 - 10,068,401 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003827524 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011352
  ENSPPAP00000011352.1
Reference Protein Sequences
RefSeq Acc Id: XP_003827524   ⟸   XM_003827476
- UniProtKB: A0A2R9A247 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000011352   ⟸   ENSPPAT00000034007
Protein Domains
Importin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034007.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  Importin_beta UniProtKB/TrEMBL
KEGG Report pps:100982939 UniProtKB/TrEMBL
NCBI Gene KPNB1 ENTREZGENE
PANTHER IMPORTIN SUBUNIT BETA-1 UniProtKB/TrEMBL
  PTHR10527 UniProtKB/TrEMBL
Pfam HEAT_EZ UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
PROSITE HEAT_REPEAT UniProtKB/TrEMBL
  IMPORTIN_B_NT UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9A247 ENTREZGENE, UniProtKB/TrEMBL