ALS2CL (ALS2 C-terminal like) - Rat Genome Database

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Gene: ALS2CL (ALS2 C-terminal like) Pan paniscus
Analyze
Symbol: ALS2CL
Name: ALS2 C-terminal like
RGD ID: 11682458
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN protein localization (ortholog); ASSOCIATED WITH genetic disease (ortholog); Progressive Microcephaly with Seizures and Cerebral and Cerebellar Atrophy (ortholog); schizophrenia (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ALS2 C-terminal-like protein-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,626,013 - 46,649,108 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,630,748 - 46,653,872 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,568,200 - 46,591,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,671,265 - 47,695,772 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,671,286 - 47,695,772 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ALS2CL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,626,013 - 46,649,108 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,630,748 - 46,653,872 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,568,200 - 46,591,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,671,265 - 47,695,772 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,671,286 - 47,695,772 (-)Ensemblpanpan1.1panPan2
ALS2CL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,668,995 - 46,693,679 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,668,995 - 46,693,704 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,710,485 - 46,735,169 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,685,683 - 46,710,175 (-)NCBINCBI36Build 36hg18NCBI36
Celera346,648,229 - 46,672,945 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,753,355 - 46,778,070 (-)NCBIHuRef
CHM1_1346,660,601 - 46,685,310 (-)NCBICHM1_1
T2T-CHM13v2.0346,685,103 - 46,709,793 (-)NCBIT2T-CHM13v2.0
Als2cl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,709,203 - 110,729,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,708,938 - 110,729,598 (+)EnsemblGRCm39 Ensembl
GRCm389110,880,120 - 110,900,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,879,870 - 110,900,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,782,678 - 110,803,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,724,990 - 110,745,340 (+)NCBIMGSCv36mm8
Celera9110,606,134 - 110,626,473 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
Als2cl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,746,498 - 119,762,824 (+)NCBIGRCr8
mRatBN7.28110,863,753 - 110,884,434 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,864,975 - 110,884,419 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08119,156,081 - 119,176,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,160,731 - 119,174,830 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,494,443 - 118,515,055 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,269,448 - 115,287,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,288,197 - 115,306,337 (+)NCBI
Celera8110,146,276 - 110,166,876 (+)NCBICelera
Cytogenetic Map8q32NCBI
Als2cl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542025,440,641 - 25,455,872 (+)NCBIChiLan1.0ChiLan1.0
ALS2CL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,067,018 - 42,091,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,066,833 - 42,088,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,982,917 - 42,007,069 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,549,320 - 42,573,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,541,177 - 42,570,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,790,574 - 41,811,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,191,649 - 42,212,661 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,472,701 - 42,493,718 (+)NCBIUU_Cfam_GSD_1.0
Als2cl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,956,940 - 200,976,633 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596506,077 - 525,746 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596506,088 - 525,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALS2CL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,596,700 - 29,618,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,596,696 - 29,618,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,829,891 - 32,901,030 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALS2CL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,093,439 - 8,116,940 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,091,528 - 8,110,881 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,033,261 - 159,058,130 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Als2cl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473074,509,658 - 74,525,221 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000035489   ⟹   ENSPPAP00000012823
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl347,671,286 - 47,695,772 (-)Ensembl
RefSeq Acc Id: XM_057301714   ⟹   XP_057157697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2246,626,013 - 46,649,102 (-)NCBI
NHGRI_mPanPan1346,630,748 - 46,653,872 (-)NCBI
RefSeq Acc Id: XR_010111538
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2246,626,013 - 46,649,108 (-)NCBI
RefSeq Acc Id: XR_010111539
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2246,626,013 - 46,649,102 (-)NCBI
RefSeq Acc Id: XR_010111540
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2246,626,013 - 46,649,100 (-)NCBI
Protein Sequences
Protein RefSeqs XP_057157697 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012823.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000012823   ⟸   ENSPPAT00000035489
RefSeq Acc Id: XP_057157697   ⟸   XM_057301714
- UniProtKB: A0A2R9A6A0 (UniProtKB/TrEMBL)
Protein Domains
VPS9


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029581 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035489.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.80 UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/TrEMBL
  Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  MORN UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
  VPS9_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100995984 UniProtKB/TrEMBL
NCBI Gene ALS2CL ENTREZGENE
PANTHER ALS2 C-TERMINAL-LIKE PROTEIN UniProtKB/TrEMBL
  ALSIN HOMOLOG UniProtKB/TrEMBL
Pfam MORN UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
PROSITE VPS9 UniProtKB/TrEMBL
SMART MORN UniProtKB/TrEMBL
Superfamily-SCOP Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
  SSF109993 UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
UniProt A0A2R9A6A0 ENTREZGENE, UniProtKB/TrEMBL