HTR3B (5-hydroxytryptamine receptor 3B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: HTR3B (5-hydroxytryptamine receptor 3B) Pan paniscus
Analyze
Symbol: HTR3B
Name: 5-hydroxytryptamine receptor 3B
RGD ID: 11675304
Description: ENCODES a protein that exhibits acetylcholine-gated monoatomic cation-selective channel activity (inferred); extracellular ligand-gated monoatomic ion channel activity (inferred); serotonin-gated monoatomic cation channel activity (inferred); INVOLVED IN cellular response to growth factor stimulus (ortholog); monoatomic cation transmembrane transport (ortholog); positive regulation of ion transmembrane transporter activity (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 5-hydroxytryptamine (serotonin) receptor 3B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,651,706 - 114,693,516 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,746,061 - 115,787,844 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,783,514 - 108,825,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,624,935 - 112,667,552 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,624,864 - 112,671,439 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HTR3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,651,706 - 114,693,516 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,746,061 - 115,787,844 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,783,514 - 108,825,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,624,935 - 112,667,552 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,624,864 - 112,671,439 (+)Ensemblpanpan1.1panPan2
HTR3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811113,898,923 - 113,949,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11113,904,796 - 113,949,079 (+)EnsemblGRCh38hg38GRCh38
GRCh3711113,775,518 - 113,819,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,280,799 - 113,322,493 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411113,280,798 - 113,322,492NCBI
Celera11110,928,462 - 110,970,153 (+)NCBICelera
Cytogenetic Map11q23.2NCBI
HuRef11109,703,741 - 109,746,039 (+)NCBIHuRef
CHM1_111113,659,109 - 113,701,462 (+)NCBICHM1_1
T2T-CHM13v2.011113,909,263 - 113,959,423 (+)NCBIT2T-CHM13v2.0
Htr3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39948,846,308 - 48,876,290 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl948,846,308 - 48,876,290 (-)EnsemblGRCm39 Ensembl
GRCm38948,935,008 - 48,964,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl948,935,008 - 48,964,990 (-)EnsemblGRCm38mm10GRCm38
MGSCv37948,743,113 - 48,773,095 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36948,686,940 - 48,716,922 (-)NCBIMGSCv36mm8
Celera946,232,548 - 46,262,426 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.54NCBI
Htr3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,175,785 - 58,204,939 (-)NCBIGRCr8
mRatBN7.2849,279,291 - 49,308,444 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,279,173 - 49,308,444 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,785,135 - 54,814,297 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,064,003 - 53,093,165 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0850,928,257 - 50,957,416 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,247,881 - 53,278,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,248,705 - 53,277,859 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,862,661 - 51,892,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,198,432 - 52,228,238 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,217,485 - 52,247,292 (-)NCBI
Celera848,836,808 - 48,865,974 (-)NCBICelera
Cytogenetic Map8q23NCBI
Htr3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,524,854 - 15,569,638 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,524,854 - 15,569,638 (+)NCBIChiLan1.0ChiLan1.0
HTR3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,361,011 - 19,393,206 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,362,382 - 19,414,912 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,285,803 - 19,320,666 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0519,382,880 - 19,437,139 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl519,378,789 - 19,435,866 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1519,446,834 - 19,500,873 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0519,348,309 - 19,402,388 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0519,395,281 - 19,449,681 (-)NCBIUU_Cfam_GSD_1.0
Htr3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,997,676 - 96,074,157 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612677,910 - 707,870 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612631,995 - 712,037 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,512,374 - 41,556,738 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,512,467 - 41,556,912 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2946,329,503 - 46,371,073 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HTR3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11105,287,738 - 105,328,793 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1105,288,865 - 105,328,714 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604320,694,212 - 20,734,265 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Htr3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247849,388,285 - 9,446,572 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247849,387,712 - 9,446,493 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003805483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide EU796520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU796560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000031561   ⟹   ENSPPAP00000008921
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11112,624,864 - 112,671,439 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000031565   ⟹   ENSPPAP00000008925
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11112,624,864 - 112,671,439 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000031567   ⟹   ENSPPAP00000008927
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11112,644,660 - 112,671,439 (+)Ensembl
RefSeq Acc Id: XM_034933736   ⟹   XP_034789627
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29114,667,118 - 114,693,516 (+)NCBI
NHGRI_mPanPan111115,761,466 - 115,787,844 (+)NCBI
Mhudiblu_PPA_v011108,802,695 - 108,825,053 (+)NCBI
RefSeq Acc Id: XM_034933738   ⟹   XP_034789629
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29114,667,131 - 114,693,516 (+)NCBI
NHGRI_mPanPan111115,761,496 - 115,787,844 (+)NCBI
Mhudiblu_PPA_v011108,802,709 - 108,825,053 (+)NCBI
RefSeq Acc Id: XM_055094858   ⟹   XP_054950833
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29114,651,706 - 114,693,516 (+)NCBI
NHGRI_mPanPan111115,746,061 - 115,787,844 (+)NCBI
RefSeq Acc Id: XM_055094859   ⟹   XP_054950834
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29114,651,706 - 114,693,516 (+)NCBI
NHGRI_mPanPan111115,746,061 - 115,787,844 (+)NCBI
RefSeq Acc Id: XM_055094860   ⟹   XP_054950835
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29114,652,549 - 114,693,516 (+)NCBI
NHGRI_mPanPan111115,746,876 - 115,787,844 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034789627   ⟸   XM_034933736
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZYV5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789629   ⟸   XM_034933738
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZYV5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000008927   ⟸   ENSPPAT00000031567
RefSeq Acc Id: ENSPPAP00000008925   ⟸   ENSPPAT00000031565
RefSeq Acc Id: ENSPPAP00000008921   ⟸   ENSPPAT00000031561
RefSeq Acc Id: XP_054950833   ⟸   XM_055094858
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054950834   ⟸   XM_055094859
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054950835   ⟸   XM_055094860
- Peptide Label: isoform X4
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027697 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031561.1 UniProtKB/TrEMBL
  ENSPPAT00000031565.1 UniProtKB/TrEMBL
  ENSPPAT00000031567.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro 5HT3_rcpt UniProtKB/TrEMBL
  5HT3_rcpt_B UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
KEGG Report pps:100984587 UniProtKB/TrEMBL
NCBI Gene HTR3B ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR 3B UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS 5HT3BRECEPTR UniProtKB/TrEMBL
  5HT3RECEPTOR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A2R8ZVD5_PANPA UniProtKB/TrEMBL
  A0A2R8ZWJ3_PANPA UniProtKB/TrEMBL
  A0A2R8ZYV5 ENTREZGENE, UniProtKB/TrEMBL
  B3VRK6_PANPA UniProtKB/TrEMBL
  B3VRL1_PANPA UniProtKB/TrEMBL
  B3VRL6_PANPA UniProtKB/TrEMBL
  B3VRM1_PANPA UniProtKB/TrEMBL
  B3VRM6_PANPA UniProtKB/TrEMBL
  B3VRN1_PANPA UniProtKB/TrEMBL
  B3VRN6_PANPA UniProtKB/TrEMBL
  B3VRP1_PANPA UniProtKB/TrEMBL
  B3VRP6_PANPA UniProtKB/TrEMBL