FBXO6 (F-box protein 6) - Rat Genome Database

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Gene: FBXO6 (F-box protein 6) Pan paniscus
Analyze
Symbol: FBXO6
Name: F-box protein 6
RGD ID: 11672353
Description: ENCODES a protein that exhibits carbohydrate binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN ERAD pathway (inferred); glycoprotein catabolic process (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); chromosome 1p36 deletion syndrome (ortholog); Familial Atrial Fibrillation 6 (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum quality control compartment (inferred); SCF ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 44; F-box only protein 6; F-box protein 44; FBXO44
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,414,856 - 10,436,406 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,632,724 - 11,641,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)NCBIpanpan1.1panPan2
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FBXO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,414,856 - 10,436,406 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,632,724 - 11,641,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)NCBIpanpan1.1panPan2
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensemblpanpan1.1panPan2
FBXO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,664,200 - 11,674,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,664,200 - 11,674,354 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,724,257 - 11,734,411 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,646,768 - 11,656,998 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,658,446 - 11,668,673NCBI
Celera110,836,207 - 10,846,475 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef110,878,308 - 10,888,516 (+)NCBIHuRef
CHM1_1111,712,136 - 11,722,413 (+)NCBICHM1_1
T2T-CHM13v2.0111,208,255 - 11,218,422 (+)NCBIT2T-CHM13v2.0
Fbxo44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,237,256 - 148,244,663 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,237,257 - 148,244,939 (-)EnsemblGRCm39 Ensembl
GRCm384148,152,799 - 148,160,183 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,152,800 - 148,160,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv374147,526,909 - 147,534,173 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364146,996,601 - 147,003,680 (-)NCBIMGSCv36mm8
Celera4150,414,144 - 150,420,371 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.67NCBI
Fbxo44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,866,517 - 163,875,928 (-)NCBIGRCr8
mRatBN7.25158,583,363 - 158,592,510 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,583,366 - 158,592,363 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5161,300,649 - 161,309,123 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05163,122,440 - 163,130,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05163,078,789 - 163,087,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,962,921 - 164,972,273 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,963,433 - 164,971,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,620,959 - 168,630,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,230,006 - 165,238,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5156,863,159 - 156,870,562 (-)NCBICelera
Cytogenetic Map5q36NCBI
Fbxo44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,204,470 - 2,210,604 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,204,470 - 2,210,604 (-)NCBIChiLan1.0ChiLan1.0
FBXO44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,557,468 - 84,562,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,089,720 - 81,095,293 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,220,535 - 85,225,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,220,537 - 85,225,672 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,969,300 - 81,974,662 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,970,031 - 82,975,586 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,032,774 - 84,038,260 (-)NCBIUU_Cfam_GSD_1.0
Fbxo44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,701,331 - 34,709,683 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936474525,862 - 532,152 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936474526,191 - 531,825 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,743,261 - 71,774,223 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,747,210 - 71,754,519 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,666,697 - 65,673,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,128,422 - 120,137,081 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,127,750 - 120,136,395 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605423,996,752 - 24,005,502 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,286,820 - 1,292,755 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248181,286,819 - 1,292,565 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003822078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003822079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000036057   ⟹   ENSPPAP00000013386
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036063   ⟹   ENSPPAP00000013392
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050891   ⟹   ENSPPAP00000028047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensembl
RefSeq Acc Id: XM_034955416   ⟹   XP_034811307
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBI
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBI
Mhudiblu_PPA_v0110,423,103 - 10,436,081 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034811307 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028047.1
Reference Protein Sequences
RefSeq Acc Id: XP_034811307   ⟸   XM_034955416
- UniProtKB: A0A2R9BIE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028047   ⟸   ENSPPAT00000050891
RefSeq Acc Id: ENSPPAP00000013392   ⟸   ENSPPAT00000036063
RefSeq Acc Id: ENSPPAP00000013386   ⟸   ENSPPAT00000036057
Protein Domains
F-box   FBA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029865 Ensembl, ENTREZGENE
  ENSPPAG00000037077 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050891.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro F-box-assoc_dom UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_only UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
NCBI Gene FBXO44 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 6 UniProtKB/TrEMBL
  PTHR12125 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBA UniProtKB/TrEMBL
PROSITE FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
SMART FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49785 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A2R9BIE4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 FBXO6  F-box protein 6  FBXO44  F-box protein 44  Symbol and/or name change 5135510 APPROVED
2020-06-11 FBXO44  F-box protein 44  FBXO6  F-box protein 6  Data merged from RGD:11732955 737654 PROVISIONAL