TGM3 (transglutaminase 3) - Rat Genome Database

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Gene: TGM3 (transglutaminase 3) Pan paniscus
Analyze
Symbol: TGM3
Name: transglutaminase 3
RGD ID: 11669100
Description: ENCODES a protein that exhibits calcium ion binding (inferred); catalytic activity (inferred); metal ion binding (inferred); INVOLVED IN keratinocyte differentiation (inferred); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease-like 1 (ortholog); FOUND IN cytoplasm (inferred); extrinsic component of cytoplasmic side of plasma membrane (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-glutamine gamma-glutamyltransferase E; transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,203,736 - 3,336,738 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,200,507 - 3,348,273 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,328,145 - 2,455,842 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,087,637 - 2,220,144 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,175,160 - 2,219,561 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TGM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,203,736 - 3,336,738 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,200,507 - 3,348,273 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,328,145 - 2,455,842 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,087,637 - 2,220,144 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,175,160 - 2,219,561 (+)Ensemblpanpan1.1panPan2
TGM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38202,296,001 - 2,341,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl202,296,001 - 2,341,079 (+)EnsemblGRCh38hg38GRCh38
GRCh37202,276,647 - 2,321,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,224,675 - 2,269,725 (+)NCBINCBI36Build 36hg18NCBI36
Build 34202,224,674 - 2,269,725NCBI
Celera202,341,537 - 2,386,652 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,226,325 - 2,271,443 (+)NCBIHuRef
CHM1_1202,276,742 - 2,321,867 (+)NCBICHM1_1
T2T-CHM13v2.0202,326,141 - 2,371,231 (+)NCBIT2T-CHM13v2.0
Tgm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,829,700 - 129,890,814 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,854,269 - 129,892,319 (+)EnsemblGRCm39 Ensembl
GRCm382129,987,794 - 130,050,399 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,012,349 - 130,050,399 (+)EnsemblGRCm38mm10GRCm38
MGSCv372129,838,110 - 129,876,135 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,703,790 - 129,740,002 (+)NCBIMGSCv36mm8
Celera2131,240,779 - 131,278,693 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
Tgm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83137,681,809 - 137,717,219 (+)NCBIGRCr8
mRatBN7.23117,228,661 - 117,264,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,228,661 - 117,264,075 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,126,350 - 121,161,931 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03129,721,966 - 129,757,547 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,382,437 - 127,418,042 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,544,783 - 122,580,836 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,544,788 - 122,580,905 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,438,622 - 127,474,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,622,727 - 117,659,103 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3116,044,936 - 116,080,248 (+)NCBICelera
Cytogenetic Map3q36NCBI
Tgm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,391,831 - 13,436,007 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,391,857 - 13,435,342 (+)NCBIChiLan1.0ChiLan1.0
TGM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,753,638 - 18,793,780 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,753,651 - 18,958,221 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,582,460 - 18,622,609 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02419,211,079 - 19,251,221 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2419,211,092 - 19,415,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,767,337 - 18,807,472 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,878,202 - 18,918,328 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02419,206,876 - 19,247,013 (-)NCBIUU_Cfam_GSD_1.0
Tgm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,827,823 - 167,893,553 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648516,259,643 - 16,296,783 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648516,259,197 - 16,325,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1733,191,914 - 33,235,952 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11733,191,901 - 33,236,065 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,610,133 - 37,615,988 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TGM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1254,189,888 - 54,236,714 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl254,189,902 - 54,221,973 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666087606,061 - 744,248 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,543,982 - 3,585,109 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,543,887 - 3,585,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000040097   ⟹   ENSPPAP00000017393
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl202,175,160 - 2,219,561 (+)Ensembl
RefSeq Acc Id: XM_034947328   ⟹   XP_034803219
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,203,736 - 3,336,738 (+)NCBI
NHGRI_mPanPan1203,200,507 - 3,340,118 (+)NCBI
Mhudiblu_PPA_v0202,328,152 - 2,455,344 (+)NCBI
RefSeq Acc Id: XM_055104896   ⟹   XP_054960871
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,253,355 - 3,336,738 (+)NCBI
NHGRI_mPanPan1203,250,172 - 3,340,118 (+)NCBI
RefSeq Acc Id: XM_063600981   ⟹   XP_063457051
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,250,260 - 3,336,738 (+)NCBI
RefSeq Acc Id: XM_063600982   ⟹   XP_063457052
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,221,687 - 3,336,738 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034803219 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960871 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457051 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457052 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000017393.1
Reference Protein Sequences
RefSeq Acc Id: XP_034803219   ⟸   XM_034947328
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AJY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000017393   ⟸   ENSPPAT00000040097
RefSeq Acc Id: XP_054960871   ⟸   XM_055104896
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063457052   ⟸   XM_063600982
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063457051   ⟸   XM_063600981
- Peptide Label: isoform X2
Protein Domains
Transglutaminase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031787 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040097.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.260.10 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Transglutaminase-like UniProtKB/TrEMBL
  Transglutaminase-like_sf UniProtKB/TrEMBL
  Transglutaminase_animal UniProtKB/TrEMBL
  Transglutaminase_AS UniProtKB/TrEMBL
  Transglutaminase_C UniProtKB/TrEMBL
  Transglutaminase_C_sf UniProtKB/TrEMBL
  Transglutaminase_N UniProtKB/TrEMBL
NCBI Gene TGM3 ENTREZGENE
PANTHER PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE UniProtKB/TrEMBL
  PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE E UniProtKB/TrEMBL
Pfam Transglut_C UniProtKB/TrEMBL
  Transglut_core UniProtKB/TrEMBL
  Transglut_N UniProtKB/TrEMBL
PIRSF TGM_EBP42 UniProtKB/TrEMBL
PROSITE TRANSGLUTAMINASES UniProtKB/TrEMBL
SMART TGc UniProtKB/TrEMBL
Superfamily-SCOP SSF49309 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A2R9AJY8 ENTREZGENE, UniProtKB/TrEMBL