CVCL_4V57 - Rat Genome Database

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Cell Line : CVCL_4V57 (NALM6/Clo) Homo sapiens

Symbol: CVCL_4V57
Name: NALM6/Clo
RGD ID: 21188999
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Selected for resistance to: ChEBI; CHEBI:681569; Clofarabine (CAFdA); Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Gender: Male
Genomic Alteration: Sequence variation: Gene fusion; HGNC; 50800; DUX4 + HGNC; 5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line); Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line)
Derived From Cell Lines: CVCL_0092 (NALM-6)
Disease(s): B-cell adult acute lymphocytic leukemia (DOID:0060592) [NCI:C9143]

References
Additional References at PubMed
PMID:25461250  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_4V57 CELLOSAURUS
Cellosaurus CVCL_4V57 CELLOSAURUS
NCIt C9143 CELLOSAURUS
Orphanet 99860 CELLOSAURUS
Wikidata Q54907446 CELLOSAURUS