CVCL_0017 - Rat Genome Database

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Cell Line : CVCL_0017 (U-698-M) Homo sapiens

Symbol: CVCL_0017
Name: U-698-M
RGD ID: 21113479
Cell Line Type: cancer cell line
Origin: Population: Caucasian
Gender: Male
Research Use: Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis by microarray; Omics: Transcriptome analysis by RNAseq
Phenotype: Doubling time: 60-65 hours (PubMed=4136723); ~48 hours (DSMZ=ACC-4); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Mutation; HGNC; 11110; ARID1A; Simple; p.Arg1446Ter (c.4336C>T); Zygosity=Heterozygous (Cosmic-CLP; DepMap); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (Cosmic-CLP; DepMap)
Groups: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE); Part of: COSMIC cell lines project; Part of: MD Anderson Cell Lines Project
Description: HLA typing: A*02:01,03:01; B*07:02,27:05; C*01:02,07:02; DQA1*01:02,03:02; DQB1*03:02,06:11; DRB1*04:01,15:01 (PubMed=26589293); Genome ancestry: African=3.7%; Native American=0%; East Asian, North=4.43%; East Asian, South=0%; South Asian=0%; European, North=69.32%; European, South=22.56% (PubMed=30894373).
Aliases: U-698; U-698 M; U-698M; U698; U698-M; U698M
Disease(s): lymphoblastic lymphoma (DOID:0080147) [NCI:C9360]
non-Hodgkin lymphoma (DOID:0060060) [ORDO:547]

References
Additional References at PubMed
PMID:2985879   PMID:3159941   PMID:3518877   PMID:3874327   PMID:4136723   PMID:4369887   PMID:20164919   PMID:25485619   PMID:25877200   PMID:26589293   PMID:27397505   PMID:28196595  
PMID:30894373   PMID:35839778  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
BioSample SAMN03471071 CELLOSAURUS
cancercelllines CVCL_0017 CELLOSAURUS
Cell Line Ontology CLO_0009462 CELLOSAURUS
Cell Model Passports SIDM00424 CELLOSAURUS
Cellosaurus CVCL_0017 CELLOSAURUS
ChEMBL-Cells CHEMBL3308280 CELLOSAURUS
ChEMBL-Targets CHEMBL2366098 CELLOSAURUS
COSMIC Samples 909777 CELLOSAURUS
Cosmic-CLP 909777 CELLOSAURUS
DepMap ACH-001680 CELLOSAURUS
DOI 10.1016/B978-0-12-221970-2.50457-5 CELLOSAURUS
DSMZ ACC-4 CELLOSAURUS
DSMZCellDive ACC-4 CELLOSAURUS
EFO EFO_0006768 CELLOSAURUS
EGA EGAS00001000610 CELLOSAURUS
  EGAS00001000978 CELLOSAURUS
GDSC 909777 CELLOSAURUS
GEO GSM1374973 CELLOSAURUS
  GSM1670558 CELLOSAURUS
LINCS_LDP LCL-1008 CELLOSAURUS
NCIt C9360 CELLOSAURUS
Orphanet 547 CELLOSAURUS
PharmacoDB U698M_1622_2019 CELLOSAURUS
PRIDE PXD030304 CELLOSAURUS
Wikidata Q54973597 CELLOSAURUS