Cell Line : CVCL_0008 (Daudi) Homo sapiens
Symbol:	CVCL_0008
Name:	Daudi
RGD ID:	21113450
Cell Line Type:	cancer cell line
Origin:	Population: African; Kenyan; Transformant: Epstein-Barr virus (EBV)(NCBI-Taxonomy; 10376); Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178; Cell type: B-cell; CL=CL_0000236.
Gender:	Male
Research Use:	Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis by microarray; Omics: Transcriptome analysis by RNAseq; Omics: Virome analysis using RNAseq
Availability:	Discontinued: ATCC; CRL-7917; true
Phenotype:	Doubling time: 23.7 hours (PubMed=8847894); ~48 hours (DSMZ=ACC-78); Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526); Microsatellite instability: Instable (MSI-low) (Sanger)
Genomic Alteration:	Sequence variation: Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (PubMed=3116544; PubMed=6806672); Sequence variation: Mutation; HGNC; 914; B2M; Simple; p.Met1Ile (c.3G>C); Zygosity=Homozygous (PubMed=8197130; PubMed=11894933; Cosmic-CLP; DepMap); Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Ala5_Ala80del (c.14_241del228); Zygosity=Homozygous (ATCC); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (Cosmic-CLP; DepMap)
Caution:	Caution: TP53 mutation indicated incorrectly as being at c.637C>T in PubMed=2052620
Groups:	Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel; Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE); Part of: COSMIC cell lines project; Part of: Human variation panel; Part of: LL-100 blood cancer cell line panel; Part of: MD Anderson Cell Lines Project
Description:	HLA typing: A*01:02,66:01; B*35:01,58:01; C*03:02,06:02; DQA1*01:03,01:03; DQB1*06:13,06:13; DRB1*13:02,03:27 (PubMed=25960936); HLA typing: A*01:02,66:01; B*58:01,58:01; C*03:02,06:02 (PubMed=26589293); HLA typing: A*01:02,66:01; B*58:01:01:01,58:02:01; C*03:02:02:01,06:02; DPA1*01:03:01,02:01:01:01; DPB1*02:01:02:01,106:01; DQA1*01:02,01:03; DQB1*06:04:01,06:02; DRB1*13:01:01,13:02:01; DRB3*02:02,03:01:01; DRB6*02 (IPD-IMGT/HLA=10471); HLA typing: A*01:02,66:01:01; B*58:01:01,58:02:01; C*03:02:02,06:02:01; DPA1*01:03:01,02:01:01; DPB1*02:01:02,106:01; DQA1*01:02:01,01:03:01; DQB1*06:09:01,06:02:01; DRA*01:01:01,01:02:03; DRB1*13:01:01,13:02:01 (DSMZCellDive=ACC-78); Genome ancestry: African=91.6%; Native American=0.12%; East Asian, North=2.24%; East Asian, South=0%; South Asian=1.3%; European, North=0%; European, South=4.74% (PubMed=30894373)
Child Cell Lines:	CVCL_5I55 (RST2) CVCL_6220 (Daudi-TG) CVCL_B5KW (Daudi-Luc2) CVCL_UF09 (DIF10) CVCL_UF10 (DIF2) CVCL_UF11 (DIF3) CVCL_UF14 (DIF8) CVCL_UF15 (DIF9) CVCL_ZI16 (DUT)
Aliases:	DAUDI; Duadi; GM03190; GM03190A; GM17346; GM3190; N; NK 10a; NK-10A; NK10a
Disease(s):	Burkitt lymphoma (DOID:8584) [ORDO:543]

Additional References at PubMed

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PMID:170370	PMID:216485	PMID:2052620	PMID:2140233	PMID:2470097	PMID:2985879	PMID:2998993	PMID:3026973	PMID:3034807	PMID:3080238	PMID:3116544	PMID:3159941
PMID:3518877	PMID:3785169	PMID:3874327	PMID:3905596	PMID:4122458	PMID:4174339	PMID:4178827	PMID:4321974	PMID:4364259	PMID:4878906	PMID:5021706	PMID:6186604
PMID:6200433	PMID:6231253	PMID:6286763	PMID:6500159	PMID:6547209	PMID:6582512	PMID:6592381	PMID:6806672	PMID:6935474	PMID:6954533	PMID:7316467	PMID:7849311
PMID:8197130	PMID:8301159	PMID:8515068	PMID:8558913	PMID:8558920	PMID:8847894	PMID:9192833	PMID:9473234	PMID:9510473	PMID:9685479	PMID:9737686	PMID:9738977
PMID:9973220	PMID:10739008	PMID:11021758	PMID:11226526	PMID:11894933	PMID:12145705	PMID:12967475	PMID:14504097	PMID:15028022	PMID:19358282	PMID:20164919	PMID:20215515
PMID:20454443	PMID:22460905	PMID:22885699	PMID:24590883	PMID:25355872	PMID:25485619	PMID:25877200	PMID:25960936	PMID:26589293	PMID:27397505	PMID:28196595	PMID:29892436
PMID:30285677	PMID:30629668	PMID:30894373	PMID:31068700	PMID:31160637	PMID:35839778

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External Database Links

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Database	Acc Id	Source(s)
ArrayExpress	E-MTAB-2706	CELLOSAURUS
	E-MTAB-2770	CELLOSAURUS
	E-MTAB-3610	CELLOSAURUS
	E-MTAB-38	CELLOSAURUS
	E-MTAB-7721	CELLOSAURUS
	E-MTAB-7722	CELLOSAURUS
	E-MTAB-783	CELLOSAURUS
ATCC	CCL-213	CELLOSAURUS
	CRL-7917	CELLOSAURUS
BCRC	60192	CELLOSAURUS
BioGRID_ORCS_Cell_line	1081	CELLOSAURUS
BioSample	SAMN00808283	CELLOSAURUS
	SAMN01821546	CELLOSAURUS
	SAMN01821623	CELLOSAURUS
	SAMN03472413	CELLOSAURUS
	SAMN10987948	CELLOSAURUS
BTO	BTO_0001561	CELLOSAURUS
cancercelllines	CVCL_0008	CELLOSAURUS
CCRID	1101HUM-PUMC000134	CELLOSAURUS
	1102HUM-NIFDC00053	CELLOSAURUS
	3101HUMTCHu140	CELLOSAURUS
	4201HUM-CCTCC00097	CELLOSAURUS
Cell Line Ontology	CLO_0002708	CELLOSAURUS
	CLO_0013411	CELLOSAURUS
	CLO_0013740	CELLOSAURUS
	CLO_0050991	CELLOSAURUS
Cell Model Passports	SIDM00845	CELLOSAURUS
CelloPub	CLPUB00447	CELLOSAURUS
Cellosaurus	CVCL_0008	CELLOSAURUS
ChEMBL-Cells	CHEMBL3307579	CELLOSAURUS
ChEMBL-Targets	CHEMBL614281	CELLOSAURUS
Coriell	GM03190	CELLOSAURUS
	GM17346	CELLOSAURUS
COSMIC Samples	1019315	CELLOSAURUS
	1037701	CELLOSAURUS
	1070708	CELLOSAURUS
	1071878	CELLOSAURUS
	1086326	CELLOSAURUS
	1093789	CELLOSAURUS
	1118470	CELLOSAURUS
	1176616	CELLOSAURUS
	1191690	CELLOSAURUS
	1517663	CELLOSAURUS
	1995384	CELLOSAURUS
	2649240	CELLOSAURUS
	2759407	CELLOSAURUS
	2760061	CELLOSAURUS
	2814537	CELLOSAURUS
	2815216	CELLOSAURUS
	2823073	CELLOSAURUS
	687838	CELLOSAURUS
	906831	CELLOSAURUS
	919135	CELLOSAURUS
	929815	CELLOSAURUS
	931102	CELLOSAURUS
	932762	CELLOSAURUS
	991548	CELLOSAURUS
	996304	CELLOSAURUS
	998716	CELLOSAURUS
Cosmic-CLP	906831	CELLOSAURUS
DepMap	ACH-000786	CELLOSAURUS
DSMZ	ACC-78	CELLOSAURUS
DSMZCellDive	ACC-78	CELLOSAURUS
ECACC	85011437	CELLOSAURUS
	94071449	CELLOSAURUS
EFO	EFO_0002169	CELLOSAURUS
EGA	EGAS00001000610	CELLOSAURUS
	EGAS00001000978	CELLOSAURUS
	EGAS00001002554	CELLOSAURUS
GDSC	906831	CELLOSAURUS
GEO	GSM1374459	CELLOSAURUS
	GSM1669726	CELLOSAURUS
	GSM3150242	CELLOSAURUS
	GSM862859	CELLOSAURUS
	GSM862860	CELLOSAURUS
	GSM862861	CELLOSAURUS
	GSM862862	CELLOSAURUS
	GSM886973	CELLOSAURUS
	GSM888042	CELLOSAURUS
	GSM960117	CELLOSAURUS
	GSM960118	CELLOSAURUS
	GSM960119	CELLOSAURUS
	GSM960120	CELLOSAURUS
	GSM99381	CELLOSAURUS
ICLC	HTL95024	CELLOSAURUS
IGRhCellID	Daudi	CELLOSAURUS
IHW	IHW09366	CELLOSAURUS
IPD-IMGT/HLA	10471	CELLOSAURUS
JCRB	JCRB9071	CELLOSAURUS
KCLB	10213	CELLOSAURUS
LiGeA	CCLE_233	CELLOSAURUS
LINCS_LDP	LCL-2018	CELLOSAURUS
Lonza	490	CELLOSAURUS
NCIt	C27694	CELLOSAURUS
Orphanet	543	CELLOSAURUS
PharmacoDB	Daudi_283_2019	CELLOSAURUS
PRIDE	PXD004181	CELLOSAURUS
	PXD012087	CELLOSAURUS
	PXD030304	CELLOSAURUS
Progenetix	CVCL_0008	CELLOSAURUS
RCB	RCB1640	CELLOSAURUS
Wikidata	Q54828579	CELLOSAURUS

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