Cell Line : CVCL_B7AM (NALM-6/H) Homo sapiens
Symbol:	CVCL_B7AM
Name:	NALM-6/H
RGD ID:	151667410
Cell Line Type:	cancer cell line
Origin:	Population: Caucasian; Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Gender:	Male
Characteristics:	Characteristics: Cultured under hypoxia for 5 weeks (PubMed=34823530)
Genomic Alteration:	Sequence variation: Gene fusion; HGNC; 50800; DUX4 + HGNC; 5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line); Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line)
Derived From Cell Lines:	CVCL_0092 (NALM-6)
Disease(s):	B-cell adult acute lymphocytic leukemia (DOID:0060592) [NCI:C9143]

Additional References at PubMed

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PMID:34823530

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External Database Links

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Database	Acc Id	Source(s)
cancercelllines	CVCL_B7AM	CELLOSAURUS
Cellosaurus	CVCL_B7AM	CELLOSAURUS
NCIt	C9143	CELLOSAURUS
Orphanet	99860	CELLOSAURUS
Wikidata	Q112129400	CELLOSAURUS

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