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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350605
Species: Homo sapiens
RGD Object: Gene
Symbol: POU5F1
Name: POU class 5 homeobox 1
Acc ID: CHEBI:9774
Term: tubocurarine
Definition: A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.
Chemical ID: MESH:D014403
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
POU5F1decreases expressionISOPou5f1 (Mus musculus)6480464CTDTubocurarine results in decreased expression of POU5F1 mRNAPMID:15612475
POU5F1multiple interactionsISOPou5f1 (Mus musculus)6480464CTDTubocurarine inhibits the reaction [Nicotine results in increased expression of POU5F1 mRNA]PMID:15749260
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