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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736218
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2d22
Name: cytochrome P450, family 2, subfamily d, polypeptide 22
Acc ID: CHEBI:9199
Term: sophoranone
Definition: A dihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7 and 4' and prenyl groups at positions 3' and 5' respectively.
Chemical ID: MESH:C461819
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d22decreases activityISOCYP2D6 (Homo sapiens)6480464CTDsophoranone results in decreased activity of CYP2D6 proteinPMID:29753067
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