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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359315
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Maf1
Name: MAF1 homolog, negative regulator of RNA polymerase III
Acc ID: CHEBI:9130
Term: sevoflurane
Definition: An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Chemical ID: MESH:C009250
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maf1decreases expressionISOMaf1 (Mus musculus)6480464CTDSevoflurane results in decreased expression of MAF1 mRNA; Sevoflurane results in decreased expression of MAF1 proteinPMID:35430185
Maf1multiple interactionsISOMaf1 (Mus musculus)6480464CTDdorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of ARG1 mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of MRC1 mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of TGFB1 mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in decreased secretion of IL10 protein]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of CD86 mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of IFNG mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of NOS2 mRNA]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of IL1B protein]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of IL6 protein]]; dorsomorphin inhibits the reaction [MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of TNF protein]]; MAF1 protein affects the reaction [Sevoflurane affects the localization of NFE2L2 protein]; MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of ARG1 mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of MRC1 mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in decreased expression of TGFB1 mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in decreased secretion of IL10 protein]; MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of CD86 mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of IFNG mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in increased expression of NOS2 mRNA]; MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of IL1B protein]; MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of IL6 protein]; MAF1 protein inhibits the reaction [Sevoflurane results in increased secretion of TNF protein]PMID:35430185
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