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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11275
Species: Mus musculus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:9130
Term: sevoflurane
Definition: An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Chemical ID: MESH:C009250
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2decreases expressionISOCcl2 (Rattus norvegicus)6480464CTDsevoflurane results in decreased expression of CCL2 mRNAPMID:15564938
Ccl2increases expressionISOCcl2 (Rattus norvegicus)6480464CTDSevoflurane results in increased expression of CCL2 proteinPMID:31713761
Ccl2multiple interactionsISOCcl2 (Rattus norvegicus)6480464CTD3-(1-azepanylsulfonyl)-N-(3-bromphenyl)benzamide inhibits the reaction [Sevoflurane results in increased expression of CCL2 protein]PMID:31713761
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