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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:90705
Term: SB 203580
Definition: A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.
Chemical ID: MESH:C093642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1multiple interactionsISOSqstm1 (Rattus norvegicus)6480464CTDSB 203580 inhibits the reaction [fenvalerate results in decreased expression of SQSTM1 protein]PMID:31734597
Sqstm1multiple interactionsISOSQSTM1 (Homo sapiens)6480464CTDSB 203580 inhibits the reaction [sodium arsenite affects the expression of SQSTM1 protein]PMID:34861471
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