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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735171
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr3
Name: toll-like receptor 3
Acc ID: CHEBI:8711
Term: quinacrine
Definition: A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Chemical ID: MESH:D011796
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr3multiple interactionsISOTLR3 (Homo sapiens)6480464CTDQuinacrine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]PMID:21398612
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