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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod1
Name: superoxide dismutase 1
Acc ID: CHEBI:82664
Term: iron(0)
Definition: An elemental iron in which the atom has an oxidation state of zero.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod1multiple interactionsEXP 6480464CTD[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD1 protein]PMID:22534743
Sod1affects abundanceISOSod1 (Mus musculus)6480464CTDSOD1 protein affects the abundance of IronPMID:19482077
Sod1multiple interactionsISOSod1 (Mus musculus)6480464CTD[Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]PMID:17194920
Sod1multiple interactionsISOSOD1 (Homo sapiens)6480464CTDSOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased uptake of Iron]PMID:16272461
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