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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313526
Species: Mus musculus
RGD Object: Gene
Symbol: Mki67
Name: antigen identified by monoclonal antibody Ki 67
Acc ID: CHEBI:81760
Term: difenoconazole
Definition: A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms.
Chemical ID: MESH:C115058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mki67increases expressionISOMki67 (Rattus norvegicus)6480464CTDdifenoconazole results in increased expression of MKI67 proteinPMID:34519103
Mki67multiple interactionsISOMki67 (Rattus norvegicus)6480464CTDginger extract inhibits the reaction [difenoconazole results in increased expression of MKI67 protein]PMID:34519103
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