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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc5a5
Name: solute carrier family 5 member 5
Acc ID: CHEBI:81520
Term: 2,3',4,4',5-Pentachlorobiphenyl
Definition: A pentachlorobiphenyl that has formula C12H5Cl5.
Chemical ID: MESH:C070055
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc5a5decreases expressionEXP 6480464CTD2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 proteinPMID:26519956 PMID:36450500
Slc5a5multiple interactionsEXP 6480464CTDalpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 protein]PMID:26519956
Slc5a5decreases expressionISOSLC5A5 (Homo sapiens)6480464CTD2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 mRNA; 2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 proteinPMID:25644787
Slc5a5multiple interactionsISOSLC5A5 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 protein]PMID:25644787
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