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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1decreases expressionISOSQSTM1 (Homo sapiens)6480464CTD2-tert-butylhydroquinone results in decreased expression of SQSTM1 mRNAPMID:35724838
Sqstm1increases expressionISOSqstm1 (Rattus norvegicus)6480464CTD2-tert-butylhydroquinone results in increased expression of SQSTM1 proteinPMID:31726083
Sqstm1increases expressionISOSQSTM1 (Homo sapiens)6480464CTD2-tert-butylhydroquinone results in increased expression of SQSTM1 proteinPMID:23589329
Sqstm1multiple interactionsISOSqstm1 (Rattus norvegicus)6480464CTD[thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of SQSTM1 proteinPMID:31726083
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