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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:7596
Term: nitroprusside
Definition: An iron coordination entity that has formula C5FeN6O.
Chemical ID: MESH:D009599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2decreases expressionEXP 6480464CTDNitroprusside results in decreased expression of NFE2L2 proteinPMID:29353218
Nfe2l2multiple interactionsEXP 6480464CTDNitroprusside inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]PMID:29353218
Nfe2l2decreases expressionISONFE2L2 (Homo sapiens)6480464CTDNitroprusside results in decreased expression of NFE2L2 proteinPMID:31066958
Nfe2l2decreases expressionISONfe2l2 (Mus musculus)6480464CTDNitroprusside results in decreased expression of NFE2L2 proteinPMID:29353218
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTDDeferoxamine inhibits the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; GOSR1 protein affects the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; MAPK3 protein affects the reaction [GOSR1 protein affects the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]]PMID:31066958
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDNitroprusside inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]PMID:29353218
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