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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61813
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ftl1
Name: ferritin light chain 1
Acc ID: CHEBI:75832
Term: iron(2+) sulfate (anhydrous)
Definition: A compound of iron and sulfate in which the ratio of iron(2+) to sulfate ions is 1:1. Various hydrates occur naturally - most commonly the heptahydrate, which loses water to form the tetrahydrate at 57degreeC and the monohydrate at 65degreeC.
Chemical ID: MESH:C020748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ftl1increases expressionEXP 6480464CTDferrous sulfate results in increased expression of FTL1 proteinPMID:28993186
Ftl1increases expressionISOFTL (Homo sapiens)6480464CTDferrous sulfate results in increased expression of FTL proteinPMID:16039939
Ftl1multiple interactionsISOFTL (Homo sapiens)6480464CTD[nickel chloride results in increased activity of ACO1 protein] inhibits the reaction [ferrous sulfate results in increased expression of FTL protein]PMID:16039939
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