GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ATF3 | increases expression | EXP | | 6480464 | CTD | sulindac sulfide results in increased expression of ATF3 mRNA; sulindac sulfide results in increased expression of ATF3 protein | PMID:12734198 PMID:15897233 PMID:16079301 PMID:16184548 PMID:21554132 PMID:24440808 | ATF3 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; [sulindac sulfide results in increased phosphorylation of MAPK1 protein] which results in increased expression of ATF3 protein; [sulindac sulfide results in increased phosphorylation of MAPK3 protein] which results in increased expression of ATF3 protein; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; MAP2K1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA] | PMID:16079301 | | ||||||||||||||||||||||
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