GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | platycodin D results in increased activity of CASP3 protein | PMID:26184636 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | platycodin D results in increased activity of CASP3 protein | PMID:16631160 PMID:18804340 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | platycodin D results in increased cleavage of CASP3 protein | PMID:23236765 PMID:24048756 PMID:25532840 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [MK 2206 co-treated with platycodin D] results in increased activity of CASP3 protein; [platycodin D co-treated with Imatinib Mesylate] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [platycodin D results in increased activity of CASP3 protein] | PMID:18804340 PMID:27897231 PMID:29552859 | | ||||||||||||||||||||||
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