GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NAMPT | affects expression | EXP | | 6480464 | CTD | Metformin affects the expression of NAMPT mRNA; Metformin affects the expression of NAMPT protein | PMID:23315983 | NAMPT | multiple interactions | EXP | | 6480464 | CTD | SIRT1 protein affects the reaction [Metformin affects the expression of NAMPT mRNA] | PMID:23315983 | NAMPT | increases expression | ISO | Nampt (Rattus norvegicus) | 6480464 | CTD | Metformin results in increased expression of NAMPT mRNA | PMID:25596134 | NAMPT | multiple interactions | ISO | Nampt (Rattus norvegicus) | 6480464 | CTD | Metformin inhibits the reaction [Letrozole results in increased expression of NAMPT mRNA] | PMID:32298659 | |
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