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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3369
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:66395
Term: miquelianin
Definition: A quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities.
Chemical ID: MESH:C443401
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparamultiple interactionsEXP 6480464CTDquercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein]PMID:26190035
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