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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307370
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh5
Name: cadherin 5
Acc ID: CHEBI:6601
Term: lycorine
Definition: An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity.
Chemical ID: MESH:C015330
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh5decreases expressionISOCDH5 (Homo sapiens)6480464CTDlycorine results in decreased expression of CDH5 mRNAPMID:23376478
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