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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628649
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mc2r
Name: melanocortin 2 receptor
Acc ID: CHEBI:6367
Term: lamotrigine
Definition: A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.
Chemical ID: MESH:C047781
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mc2rincreases response to substanceISOMC2R (Homo sapiens)6480464CTDMC2R protein results in increased susceptibility to lamotriginePMID:20021991
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