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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620761
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Notch3
Name: notch receptor 3
Acc ID: CHEBI:53621
Term: chloromethylisothiazolinone
Definition: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product Kathon(TM).
Chemical ID: MESH:C011421
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Notch3increases expressionISONOTCH3 (Homo sapiens)6480464CTD5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of NOTCH3 mRNAPMID:20713136
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