GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | increases expression | EXP | | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased expression of TNF mRNA | PMID:20371970 | TNF | multiple interactions | EXP | | 6480464 | CTD | [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of TNF protein | PMID:24964617 | TNF | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased expression of TNF mRNA; Toluene 2,4-Diisocyanate results in increased expression of TNF protein | PMID:11467998 PMID:12356572 PMID:12789230 PMID:16516891 PMID:17014439 PMID:17641053 PMID:18652873 PMID:20219652 PMID:28826779 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | 4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TNF mRNA]; 4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TNF protein]; bisphenol A promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of and results in increased secretion of TNF protein]; epigallocatechin gallate inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TNF protein]; ICAM1 protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of TNF protein]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 mRNA]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 mRNA]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of LTA mRNA]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of LTB mRNA]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of TNF mRNA]; TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of XCL1 mRNA]; Toluene 2,4-Diisocyanate results in increased expression of and results in increased secretion of TNF protein | PMID:12356572 PMID:12789230 PMID:16516891 PMID:17014439 PMID:29846729 | | ||||||||||||||||||||||
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