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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735430
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1R1
Name: interleukin 1 receptor type 1
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1R1increases expressionISOIl1r1 (Rattus norvegicus)6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNAPMID:17449585
IL1R1multiple interactionsISOIl1r1 (Rattus norvegicus)6480464CTDActive Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]PMID:17449585
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