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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3931
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ucp1
Name: uncoupling protein 1
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp1increases expressionEXP 6480464CTDAlitretinoin results in increased expression of UCP1 mRNAPMID:12414803
Ucp1multiple interactionsEXP 6480464CTD2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Alitretinoin results in increased expression of UCP1 mRNA]; Glutathione inhibits the reaction [Alitretinoin results in increased expression of UCP1 mRNA]PMID:12414803
Ucp1increases expressionISOUcp1 (Mus musculus)6480464CTDAlitretinoin results in increased expression of UCP1 mRNAPMID:10600643
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