GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | decreases expression | EXP | | 6480464 | CTD | Nanotubes, Carbon results in decreased expression of PTGS2 mRNA | PMID:26589480 | Ptgs2 | affects expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Nanotubes, Carbon affects the expression of PTGS2 mRNA | PMID:23845593 | Ptgs2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Nanotubes, Carbon analog results in increased expression of PTGS2 mRNA; Nanotubes, Carbon results in increased expression of PTGS2 mRNA; Nanotubes, Carbon results in increased expression of PTGS2 protein | PMID:22571318 PMID:25554681 | Ptgs2 | increases response to substance | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | PTGS2 gene mutant form results in increased susceptibility to Nanotubes, Carbon | PMID:23642096 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | [Nanotubes, Carbon co-treated with PTGS2 gene mutant form] results in increased abundance of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Nanotubes, Carbon] which results in increased abundance of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Nanotubes, Carbon] which results in increased abundance of Thromboxane B2; fucoidan inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]]; Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]; Poloxamer inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]]; U 0126 inhibits the reaction [Nanotubes, Carbon results in increased expression of PTGS2 protein] | PMID:17709331 PMID:22571318 PMID:23642096 | | ||||||||||||||||||||||
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