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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10increases expressionISOIl10 (Mus musculus)6480464CTDNanotubes, Carbon results in increased expression of IL10 mRNA; Nanotubes, Carbon results in increased expression of IL10 proteinPMID:17660506 PMID:19428951
Il10increases expressionISOIL10 (Homo sapiens)6480464CTDNanotubes, Carbon results in increased expression of IL10 mRNA; Nanotubes, Carbon results in increased expression of IL10 proteinPMID:22076105 PMID:27475286
Il10increases secretionISOIl10 (Mus musculus)6480464CTDNanotubes, Carbon results in increased secretion of IL10 proteinPMID:19150385 PMID:22081859
Il10multiple interactionsISOIl10 (Mus musculus)6480464CTD[Nanotubes, Carbon co-treated with Ovalbumin] results in increased expression of IL10 mRNA; STAT1 protein affects the reaction [[Nanotubes, Carbon co-treated with Ovalbumin] results in increased expression of IL10 mRNA]PMID:25807359
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDLipopolysaccharides promotes the reaction [Nanotubes, Carbon results in increased expression of IL10 protein]; Nanotubes, Carbon inhibits the reaction [TLR2 protein results in increased secretion of IL10 protein]PMID:23266719 PMID:27475286
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