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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:47977
Term: 2-amino-2-deoxy-D-glucopyranose
Definition: A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3decreases expressionEXP 6480464CTDGlucosamine results in decreased expression of DDIT3 mRNAPMID:17178593
Ddit3increases expressionEXP 6480464CTDGlucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 proteinPMID:30602124
Ddit3multiple interactionsEXP 6480464CTD4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein]PMID:30602124
Ddit3increases expressionISODDIT3 (Homo sapiens)6480464CTDGlucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 proteinPMID:16380481 PMID:33812996
Ddit3multiple interactionsISODDIT3 (Homo sapiens)6480464CTDNUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]PMID:33812996
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