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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:46677
Term: amphibole asbestos
Definition: A class of asbestos minerals that includes silicates of magnesium, iron, calcium, and sodium.
Chemical ID: MESH:D017636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationEXP 6480464CTDAsbestos, Amphibole results in increased phosphorylation of MAPK3 proteinPMID:22168577
Mapk3multiple interactionsEXP 6480464CTDferric chloride inhibits the reaction [Asbestos, Amphibole results in increased phosphorylation of MAPK3 protein]PMID:22168577
Mapk3increases phosphorylationISOMAPK3 (Homo sapiens)6480464CTDAsbestos, Amphibole results in increased phosphorylation of MAPK3 proteinPMID:23017228
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