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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620707
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tff1
Name: trefoil factor 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tff1decreases expressionISOTFF1 (Homo sapiens)6480464CTDtrichostatin A results in decreased expression of TFF1 mRNAPMID:22476901
Tff1multiple interactionsISOTFF1 (Homo sapiens)6480464CTD[Decitabine co-treated with trichostatin A] affects the expression of TFF1 mRNA; [Decitabine co-treated with trichostatin A] results in increased expression of TFF1 mRNA; [Raloxifene Hydrochloride co-treated with trichostatin A] results in decreased expression of TFF1 mRNA; trichostatin A inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of TFF1 mRNA]PMID:17533736 PMID:18264725 PMID:22476901
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