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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1298347
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP7
Name: caspase 7
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP7increases expressionEXP 6480464CTDtrichostatin A results in increased expression of CASP7 mRNAPMID:24935251
CASP7multiple interactionsEXP 6480464CTD[Bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP7 proteinPMID:16904634
CASP7decreases expressionISOCasp7 (Rattus norvegicus)6480464CTDtrichostatin A results in decreased expression of CASP7 mRNAPMID:23558232
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