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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71103
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc27a2
Name: solute carrier family 27 member 2
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc27a2affects expressionISOSlc27a2 (Mus musculus)6480464CTDMethotrexate affects the expression of SLC27A2 mRNAPMID:18502557
Slc27a2affects response to substanceISOSLC27A2 (Homo sapiens)6480464CTDSLC27A2 protein affects the susceptibility to MethotrexatePMID:16217747
Slc27a2increases expressionISOSLC27A2 (Homo sapiens)6480464CTDMethotrexate results in increased expression of SLC27A2 mRNAPMID:17400583
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