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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314001
Species: Homo sapiens
RGD Object: Gene
Symbol: PINK1
Name: PTEN induced kinase 1
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PINK1increases expressionEXP 6480464CTDGlucose results in increased expression of PINK1 mRNAPMID:33962019
PINK1multiple interactionsEXP 6480464CTD[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA]PMID:33962019
PINK1decreases expressionISOPink1 (Rattus norvegicus)6480464CTDGlucose results in decreased expression of PINK1 proteinPMID:35243728
PINK1multiple interactionsISOPink1 (Rattus norvegicus)6480464CTDInositol inhibits the reaction [Glucose results in decreased expression of PINK1 protein]PMID:35243728
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