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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2126
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apex1
Name: apurinic/apyrimidinic endodeoxyribonuclease 1
Acc ID: CHEBI:38728
Term: monocrotophos
Definition: An alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate.
Chemical ID: MESH:D008999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apex1increases expressionISOAPEX1 (Homo sapiens)6480464CTDMonocrotophos results in increased expression of APEX1 mRNAPMID:28887667
Apex1multiple interactionsISOAPEX1 (Homo sapiens)6480464CTDMonocrotophos results in increased expression of and affects the localization of APEX1 proteinPMID:28887667
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