GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | increases expression | EXP | | 6480464 | CTD | 3-methyladenine results in increased expression of SQSTM1 protein | PMID:33462182 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | 3-methyladenine inhibits the reaction [anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein] | PMID:33462182 PMID:34051206 PMID:36708882 | Sqstm1 | increases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | 3-methyladenine results in increased expression of SQSTM1 protein | PMID:24833599 | Sqstm1 | increases expression | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | 3-methyladenine results in increased expression of SQSTM1 protein | PMID:20574048 PMID:29781141 PMID:32702505 PMID:34281243 PMID:34405320 PMID:34580807 PMID:36193553 | Sqstm1 | multiple interactions | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | 3-methyladenine inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]] | PMID:29128638 PMID:29518472 PMID:31734597 PMID:35066094 | Sqstm1 | multiple interactions | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | 3-methyladenine affects the reaction [ginsenoside Rg3 affects the reaction [Cisplatin affects the expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [ABBV-744 results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Ivermectin results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [LGALS1 protein results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Particulate Matter results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Potassium Dichromate results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Quercetin results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; 3-methyladenine inhibits the reaction [sepantronium results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [Silicon Dioxide results in decreased expression of SQSTM1 protein]; 3-methyladenine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased degradation of SQSTM1 protein]; 3-methyladenine promotes the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein]; 3-methyladenine promotes the reaction [ovatodiolide results in increased expression of SQSTM1 protein]; [3-methyladenine co-treated with bisphenol A] results in increased expression of SQSTM1 protein; Ropivacaine inhibits the reaction [3-methyladenine results in increased expression of SQSTM1 protein] | PMID:22927544 PMID:25943029 PMID:28025121 PMID:28251795 PMID:29307831 PMID:29518472 PMID:29781141 PMID:29923297 PMID:30362509 PMID:30365942 PMID:31837377 PMID:32061152 PMID:32569804 PMID:32702505 PMID:34281243 PMID:34423507 PMID:34481905 PMID:34904774 PMID:36193553 PMID:36336208 PMID:37769529 PMID:38000454 | | ||||||||||||||||||||||
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