GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | S1pr2 | increases activity | EXP | | 6480464 | CTD | sphingosine 1-phosphate results in increased activity of S1PR2 protein | PMID:22406263 | S1pr2 | increases expression | EXP | | 6480464 | CTD | sphingosine 1-phosphate results in increased expression of S1PR2 protein | PMID:37169277 | S1pr2 | multiple interactions | EXP | | 6480464 | CTD | [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein]; [JTE 013 binds to and results in decreased activity of S1PR2 protein] results in decreased susceptibility to [sphingosine 1-phosphate co-treated with Glucose]; [JTE 013 binds to and results in decreased activity of S1PR2 protein] which results in decreased susceptibility to sphingosine 1-phosphate; [sphingosine 1-phosphate results in increased activity of S1PR2 protein] which results in increased expression of FN1; JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of S1PR2 protein]; sphingosine 1-phosphate promotes the reaction [dibutyldichlorotin results in increased expression of S1PR2 protein] | PMID:22406263 PMID:37169277 | S1pr2 | increases uptake | ISO | S1PR2 (Homo sapiens) | 6480464 | CTD | sphingosine 1-phosphate results in increased uptake of S1PR2 protein | PMID:26518876 | S1pr2 | multiple interactions | ISO | S1PR2 (Homo sapiens) | 6480464 | CTD | S1PR2 mutant form inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] | PMID:18612546 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |