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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345007
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
Acc ID: CHEBI:36696
Term: 1,2,3,5-tetrachlorobenzene
Definition: A tetrachlorobenzene carrying chloro groups at positions 1, 2, 3 and 5.
Chemical ID: MESH:C030387
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2E1increases metabolic processingEXP 6480464CTDCYP2E1 protein results in increased metabolism of 1,2,3,5-tetrachlorobenzenePMID:7747284
CYP2E1increases oxidationEXP 6480464CTDCYP2E1 protein results in increased oxidation of 1,2,3,5-tetrachlorobenzenePMID:7747284
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