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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346751
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2B6
Name: cytochrome P450 family 2 subfamily B member 6
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2B6decreases expressionISOCyp2b10 (Mus musculus)6480464CTDcobaltous chloride results in decreased expression of CYP2B10 mRNAPMID:21139344
CYP2B6decreases expressionISOCyp2b3 (Rattus norvegicus)6480464CTDcobaltous chloride results in decreased expression of CYP2B3 mRNAPMID:24386269
CYP2B6increases expressionISOCyp2b10 (Mus musculus)6480464CTDcobaltous chloride results in increased expression of CYP2B10 mRNAPMID:23528251
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